Method of determining the presence and titers of anti HIV-1 ag27

Details Method of determining the presence and titers of anti HIV-1 ag27 Method of determining the presence and titers of anti HIV-1 ag27

1992-08-24

1994-10-04

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435974, 436518, 436536, 436 86, 436 87, 930221, C12Q 170, G01N 33543, G01N 33536, G01N 3300

Patent

active

053525760

ABSTRACT:
Disclosed is a method for determining the presence in mammalian serum of antibodies against specific strains of HIV through the use of SP-10 peptides. The method incorporates the use of SP-10 peptides derived from the following HIV strains: IIIB, MN, RF, SC, WMJ-1, WMJ-2, WMJ-3, ARV-2, and LAV-1.

REFERENCES:
patent: 4520113 (1985-05-01), Gallo et al.
patent: 4659678 (1987-03-01), Forrest et al.
patent: 4725669 (1988-02-01), Essex et al.
patent: 4812556 (1989-03-01), Vahlne et al.
patent: 4956273 (1990-09-01), Kennedy et al.
patent: 5013548 (1991-05-01), Haynes et al.
patent: 5019387 (1991-05-01), Haynes et al.
patent: 5081226 (1992-01-01), Berzofsky et al.
Ratner et al, "Complete Nucleotide Sequence of the AIDS Virus, HTLV-III," Nature, vol. 313, pp. 277-284, 1985.
Palker et al, "A Conserved Region at the COOH Terminus of Human Immunodeficiency Virus gp 120 Envelop Protein Contains an Immunodominant Epitope", Proc. Natl. Acad. Sci. USA. vol. 84, pp. 2479-2483, 1987.
Peter Newmark, "Problems with AIDS Vaccines" Nature, vol. 324, pp. 304-305, 1986.
Colin Norman, "AIDS Virus Presents Moving Target" Science, vol. 230, pp. 1357-1358, 1985.
Takahashi et al J. of Exp. Med. 170: 2023 (1989).
Palker et al. J. of Immunol. 142: 3612 (1989).
Girard et al J. of Cell. Biochem. (Abst. L415) (1990) UCLA Symp on Mol. & Cell Biol. p. 150.
Weinhold et al J. Cell. Biochem. (Abst. L550) (1990) UCLA Sump on Mol. & Cell. Biol. p. 180.
Palker et al J. Cell. Biochem (Abst. L315) (1990) UCLA Symp on Mol. & Cell Biol. p. 134.
Pert et al; Proc. Natl. Acad. Sci, USA, vol. 83, pp. 9254-9258, Dec. 1986; "Octapeptides Deducted From the Neuropeptide Receptor-Line Pattern of Antigen T4 in Brain Potently Inhibit Human Immunodeficiency Virus Receptor Binding and T-Cell Infectivity".
Sarin et al; Science, vol. 232, pp. 1135-1138, May 30, 1986; "Neutralization of HTLV-III/LAV Replication by Antiserum to Thymosin .alpha..sub.1 ".
Kennedy et al; Science, vol. 231, pp. 1556-1560, Mar. 28, 1986; "Antiserum to a Synthetic Peptide Recognizes the HTVL-III Envelope Glycoprotein".
Chanh et al; The EMBO Journal, vol, 5, No. 11; "Induction of Anti-HIV Neutralizing Antibodies by Synthetic Peptides".
Putney et al; Science, vol. 234, pp. 1392-1395, Dec. 12, 1986; HTLV-III/LAV-Neutralizing Antibodies to an E. Coli-Produced Fragment of the Virus Envelope.
Kennedy et al; The Journal of Biological Chemistry, vol. 262, No. 12, pp. 5769-5774, Apr. 25, 1967; Use of a Resin-Bound Synthetic Peptide for Identifying a Neutralizing Antigenic Determinant Associated With the Human Immunodeficiency Virus Envelope.
Cease et al; Proc. Natl. Acad. Sci USA, vol. 84, pp. 4249-4253, Jun. 1987 Helper T-Cell Antigenic Site Identification in the Acquired Immunodeficiency Syndrome Virus gp 120 Envelope Protein and Induction of Immunity in Mice to the Native Protein Using A 16-Residue Synthetic Peptide.
Ho et al; Journal of Virology, vol. 61, No. 6, pp. 2024-2028, Jun. 1987; Human Immunodeficiency Virus Neutralizing Antibodies Recognize Several Conserved Doamins on the Envelope Glycoproteins.
Krohn et al; Prc. Natl. Acad. Sci. USA, vol. 84, pp. 4994-4998, Jul. 1987 Specific Cellular Immune Response and Neutralizing Antibodies in Goats Immunized with Native or Recombinant Envelope Proteins Derived from Human T-Lymphotropic Virus Type III.sub.62 and in Human Immunodeficiency Virus-Infected Men.
Starcich et al; Cell, vol. 45, pp. 637-648, Jun. 6, 1986; Identification and Characterization of Conserved and Variable Regions in the Envelope Gene of HTLV-III/LAV, The Retrovirus of AIDS.
Robey et al; Proc. Natl. Acad. Sci. USA, vol. 83, pp. 7023-7027, Sep. 1986; Prospect for Prevention of Human Immunodeficiency Virus Infection: Purified 120-kDa Envelope Glycoprotein Induces Neutralizing Antibody.
Wang et al, Proc. Natl. Acad. Sci. USA vol. 83, pp. 6159-6163, Aug., 1986; Detection of Antibodies to Human T-Lymphotropic Virus Type III by Using a Synthetic Peptide of 21 Amino Acid Residues Corresponding to a Highly Antigenic Segment of gp41 Envelope Protein.
Sodroski et al; Nature, vol. 322, Jul. 31, 1986; Role of the HTLV-III/LAV Envelope in Syncytium Formation and Cytopathicity.
Dalgleish et al; Nature "Letters to Nature"; The CD4 (T4) Antigen is an Essential Components of the Receptor for the AIDS Retrovirus (1984).
Hu et al; Nature, vol. 320, Apr. 10, 1986; Expression of AIDS Virus Envelope Gene in Recombinant Vaccinia Viruses.
Chakrabarti et al; Nature, vol. 320, Apr. 10, 1986; Expression of the HTLV-III Envelope Gene by a Recombinant Vaccina Virus.
Zarling et al; The Journal of Immunology, vol. 139, 988-990, Aug. 15, 1987; Proliferative and Cytotoxic T Cells to AIDS Virus Glycoproteins in Chimpanzees Immunized With a Recombinant Vaccinia Virus Expressing AIDS Virus Envelope Glycoproteins.
Hu et al; Nature, vol. 328, Aug. 20, 1987; Effect of Immunization with a Vaccinia-HIV env Recombinant on HIV Infection of Chimpanzees.
Hart et al,"Synthetic Peptides Containing T and B Cell Epitopes From Human Immunodeficiency Virus Envelope gp120 Induce Anti-HIV Proliferative Responses and High Titers of Neutralizing Antibodies in Rhesus Monkeys.sup.1 ", The Journal of Immunology, vol. 145, pp. 2677 -2685, No. 8, Oct. 15, 1990.
Hart et al, "HIV Synthetic Peptides Containing T and B Cell Epitopes Induce HIV-Specific CD8+ Cytotoxic T Cell Response In Vivo", 1991 FASEB.
LaRosa et al, "Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant", Science, vol. 249 pp. 932-935, Aug. 24, 1990.
Pert et al; Proc. Natl. Acad. Sci., USA, vol. 83, pp. 9254-9258, Dec. 1986; "Octapeptides Deducted from the Neuropeptide Receptor-like Pattern of Antigen T4 in Brain Potently Inhibit Human Immunodeficiency Virus Receptor Binding and T-Cell Infectivity".
Sarin et al; Science, vol. 232, pp. 1135-1138, May 30, 1986; "Neutralization of HTLV-III/LAV Replication by Antiserum to Thymosin .alpha..sub.1 ".
Kennedy et al; Science, vol. 231, pp. 1556-1560, Mar. 28, 1986; "Antiserum to a Synthetic Peptide Recognizes the HTLV-III Envelope Glycoprotein".
Chanh et al; The EMBO Journal, vol. 5, No. 11; Induction of Anti-HIV Neutralizing Antibodies by Synthetic Peptides".
Putney et al; Science, vol. 234, pp. 1392-1395, Dec. 12, 1986; "HTLV-III/LAV-Neutralizing Antibodies to an E. Coli-Produced Fragment of the Virus Envelope".
Kennedy et al; The Journal of Biological Chemistry, vol. 262, No. 12, pp. 5769-5774, Apr. 25, 1967; "Use of Resin-Bound Synthetic Peptide for Identifying a Neutralizing Antigenic Determinant with the Human Immunodeficiency Virus Envelope".
Javaherian et al, "Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein", Proc. Natl. Acad. Sci. USA, vol. 86, pp. 6768-6772, Sep. 1989.
Takahashi et al, "Structural Requirements for Class I MHC Molecule-Cytotoxic T Cell Recognition of an Immunodominant of the Human Immunodeficiency Virus Envelope Protein", J. of Exp. Med. 170:02023 (1989).
Palker et al, "Polyvalent Human Immunodeficiency Virus Synthetic Immunogen Comprised of Envelope gp 120 T Helper Cell Sites and B Cell Neutralization Epitopes", J. of Immunol. 141:3612 (1989).
Girard et al, J. of Cell. Biochem. (Abst. L415) (1990) UCLA Sump. on Mol. and Cell Biol., p. 150.
Weinhold et al. J. Cell. Biochem. (Abst. L550) (1990) UCLA Symp. on Mol. and Cell. Biol., p. 180.
Palker et al. J. Cell. Biochem. (Abst. L315) (1990) UCLA Symp. on Mol. and Cell Biol., p. 134.
Palker et al, "Type-specific neutralization of the human immnodeficiency virus with antibodies to env-encoded synthetic peptides", Proc. Natl. Acad. Sci. USA, vol. 85, pp. 1932-1936, Mar. 1988.
Letter to the Editor, "Detection of a Fusion Peptide Sequence in the Transmembrane Protein of Human Immunodeficiency Virus", Cell, vol. 50, pp. 327-328, Jul. 31, 1987.

Affiliated with

Also associated with

Rating

Method of determining the presence and titers of anti HIV-1 ag27 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of determining the presence and titers of anti HIV-1 ag27, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of determining the presence and titers of anti HIV-1 ag27 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-580703