Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence
Patent
1991-03-07
1993-12-07
Housel, James C.
Chemistry: analytical and immunological testing
Optical result
With fluorescence or luminescence
436 56, 436 68, 436178, 436805, 422 56, 422 83, 422 86, 422 8201, 356317, 356318, 356417, G01N 170
Patent
active
052683044
ABSTRACT:
A method determines the concentration of a chemical of interest in a solution. A permeable membrane is placed in the solution and a ligand is exuded through the membrane to continually renew the ligand at the surface of the membrane which is in contact with the solution. Complexes of the ligand with the chemicals of interest are formed where the ligand renewed membrane is in contact with the solution. Illuminating the ligand renewed membrane with radiation from a distance from the membrane induces a fluorescence by the formed complexes on the ligand renewed membrane by the illuminating radiation. The fluorescence from the illuminated complexes on the ligand renewed membrane are detected from a distance from the membrane to provide a determination of the concentration of the chemical of interest in the solution.
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Inman Scott M.
Lieberman Stephen H.
Stromvall Erik J.
Daley Thomas E.
Fendelman Harvey
Housel James C.
Keough Thomas Glenn
The United States of America as represented by the Secretary of
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