Method of determining stage of sepsis

Details Method of determining stage of sepsis Method of determining stage of sepsis

1997-12-16

2000-12-12

Minnifield, Nita

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 6, 435 71, 435 72, 435 724, 435 731, 435 737, 435 25, 435 34, 435 38, 435962, 435968, 435973, 435975, 436513, 436578, 436536, 436539, 436808, 436811, C12Q 170, C12Q 110, G01N 3353, G01N 33563

Patent

active

061596833

ABSTRACT:
The invention relates to a method for staging sepsis in a patient by concurrently measuring in a sample of the patient's blood four parameters which are indicative of the stage of sepsis: 1) the level of microbial product level in the blood; 2) the level of tumor necrosis factor (TNF) response reserve; 3) the maximum oxidant production by neutrophils, and 4) the responsiveness of the patient's neutrophils to immunocomplexes. Based on determining the stage of sepsis, appropriate treatment for the patient may be identified.

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