Method of determining renal clearances

Details Method of determining renal clearances Method of determining renal clearances

1994-07-25

1996-03-19

Snay, Jeffrey R.

Chemistry: analytical and immunological testing

Heterocyclic carbon compound

Hetero-n

G01N 3350

Patent

active

055003729

ABSTRACT:
In a method of determining creatinine clearance for detecting and monitoring renal dysfunction, spot samples of urine and blood from a person are obtained. Specific gravity and creatinine concentration of the urine sample are measured. Creatinine concentration of plasma of the blood sample is also measured. Creatinine clearance is calculated as a function of the measured urine specific gravity, the measured urine creatinine concentration and the measured plasma creatinine concentration.

REFERENCES:
patent: 4529708 (1985-07-01), Stephens
patent: 4818703 (1989-04-01), Pizzolante
Robertshaw, M. "Prediction of Creatinine Clearance from Plasma Creatinine: Comparison of Five Formulae" Br. J. Clin. Pharmac., vol. 28, 275-280 (1989).
Rosano, J. G. et al. "Analytical and Biological Variability of Serum Creatinine and Creatinine Clearance" Clinical Chemistry, vol. 28, 2330-2331 (1982).
Gowans, E. et al. "Biological Variation of Serum and Urine Creatinine and Creatinine Clearance" Chemical Abstracts, vol. 109, No. 35603v, (1988).
Konishi, K. et al. "Prediction of Creatinine Clearance from the Serum Creatinine Clearance", Chemical Abstracts, vol. 102, No. 2885r. (1985).

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