Chemistry: analytical and immunological testing – Heterocyclic carbon compound – Hetero-n
Patent
1996-01-25
1997-02-11
Snay, Jeffrey
Chemistry: analytical and immunological testing
Heterocyclic carbon compound
Hetero-n
G01N 3350
Patent
active
056020384
ABSTRACT:
In a method of determining creatinine clearance for detecting and monitoring renal dysfunction, spot samples of urine and blood from a person are obtained. Specific gravity or osmolality and creatinine concentration of the urine sample are measured. Creatinine concentration of plasma of the blood sample is also measured. Creatinine clearance is calculated as a function of the measured urine specific gravity or osmolality, the measured urine creatinine concentration and the measured plasma creatinine concentration.
REFERENCES:
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patent: 4818703 (1989-04-01), Pizzolante
patent: 5500372 (1996-03-01), Kell
Robertshaw, M. "Prediction of Creatinine Clearance from Plasma Creatinine: Comparison of Five Formulae" Br. J. Clin. Pharmac., vol. 28, 275-280 (1989).
Rosano, J. G. et al. "Analytical and Biological Variability of Serum Creantinine and Creatinine Clearance" Clinical Chemistry, vol. 28, 2330-2331 (1982).
Gowans, E. et al. "Biological Variation of Serum and Urine Creatinine and Creatinine Clearance" Chemical Abstracts, vol. 109, No. 356603v, (1988).
Konishi, K. et al. "Prediction of Creatinine Clearance from the Serum Creatinine Clearance" Chemical Abstracts, vol. 102, No. 2885r (1985).
Private Clinic Laboratories Inc.
Snay Jeffrey
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