Method of determining pregnanediol in female urine and test devi

Details Method of determining pregnanediol in female urine and test devi Method of determining pregnanediol in female urine and test devi

1986-02-27

1987-12-08

Nucker, Christine M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

422 56, 435 28, 435805, 435810, 436510, 436527, 436528, 436530, 436531, 436532, 436537, 436541, 436542, 436800, 436810, 436804, 436814, 436817, G01N 3353, G01N 33552, G01N 33544, B65D 6900

Patent

active

RE0325570

ABSTRACT:
A method is provided for determining the concentration of pregnanediol glucuronide (PG) in a woman's urine which is characterized by utilization of the reagent 20.alpha.-hydroxy-4-pregnen-3-one (20-.alpha. reagent) in a form in which it reacts with antibodies binding to PG. The method is adaptable to a visual color indication test which can be performed by the woman herself as well as by laboratory analysis. The method can be used to define the period in which conception can occur, to define a post-ovulation safe period in which conception is prevented, and as an early pregnancy indicator.

REFERENCES:
patent: 4123510 (1978-10-01), Barik et al.
Chaudhri et al., J. Ster. Biochem., 13 (1980), 691-696.
DiPietro, Chem. Abstracts, 85 (1976), Abstract #89683a.
Manita et al., Chem. Abstracts, 88 (1978), Abstract #132867q.
Chatterton et al., Chem. Abstracts 96 (1982), Abstract #211087d.
Chaudri et al., J. Ster. Biochem. 16 (1982), 87-92.
Judge et al., Steroids, 31: 175-187, (1978).
Samarajeewa et al., J. Steroid Biochem., 11:1165-1171.
Collins et al., Acta Endocrinologica 90:336-348, (1979).

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