Method of determining extracellular antigens and antibodies

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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23230B, 250458, 424 12, G01N 2152, G01N 3316

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active

041338731

ABSTRACT:
Hepatitis associated antigen (HAA) in human blood serum is precipitated on HAA-specific antibodies immobilized on the inner wall of a plastic tube. A solution of HAA-specific antibodies tagged with fluorescein is held in contact with the deposited antigens until a portion of the antibodies from the solution is affixed to the antigens. The residual, tagged antibodies in the solution are exposed to a light pulse, and the resulting fluorescence is measured as an inverse indication of HAA in the blood serum.

REFERENCES:
patent: 3646346 (1972-02-01), Catt
patent: 3789116 (1974-01-01), Kay
patent: 3901654 (1975-08-01), Gross
patent: 3935074 (1976-01-01), Rubenstein
patent: 4020151 (1977-04-01), Bolz
Chemical Abstracts, 75:45466w (1971).

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