Method of determining chymase activity with secretory...

Details Method of determining chymase activity with secretory... Method of determining chymase activity with secretory...

2007-01-12

2009-08-18

Gitomer, Ralph (Department: 1657)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

C435S069200

Reexamination Certificate

active

07575888

ABSTRACT:
It is now discovered that human chymase cleaves human SLPI at a specific site and that this cleavage can be used as an indicator of chymase activity. The present invention provides methods of diagnosing a chymase-associated disease or evaluating the efficiency of a treatment of a chymase-associated disease in a human subject by measuring SLPI processing, as well as other related methods and compositions.

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