Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Reexamination Certificate
2008-01-08
2008-01-08
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
C435S006120, C435S235100, C435S320100
Reexamination Certificate
active
10505026
ABSTRACT:
The invention discloses a simple, accurate and reproducible method of determining viral particle concentration, especially for any serotype of adenovirus. More specifically, an accurate absorptivity/extinction coefficient in units of viral particles per milliliter per absorbance unit per centimeter (vp/mL-AU-cm) for a sample virus, such as adenovirus, at 260 nanometers (nm) is disclosed, as well as an ultraviolet (UV) absorbance method to determine virus particle concentrations based on this established absorptivity/extinction coefficient and absorbances at 260 nm for purified virus preparations, such as adenovirus preparations.
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Guzo David
Heber Sheldon O.
Merck & Co. , Inc.
Wu Henry P.
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