Method of determining a site of inflammation utilizing ELAM-1 li

Details Method of determining a site of inflammation utilizing ELAM-1 li Method of determining a site of inflammation utilizing ELAM-1 li

1991-04-11

1993-05-18

Maples, John S.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, A61K 4902, A61K 4900

Patent

active

052119378

ABSTRACT:
Ligands in the form of N-acetyllactosamines which bind to endothelial leukocyte adhesion molecule-1 (ELAM-1) are disclosed. The ligand compounds can be formulated into pharmaceutical compositions and/or assay compositions used to alleviate inflammation and assay for the presence of (qualitative) and amount of (quantitative) ELAM-1 and thereby determine the presence, location and degree of inflammation.

REFERENCES:
patent: 4330299 (1982-05-01), Cerami
European Search Report.
Lamblin et al., Journal of Biological Chemistry (1984) 259(14):9051-9058.
Stanley et al., Journal of Biological Chemistry (1988) 263(23):11374-11381.
Michalski et al., FEBS Letters (1977) 79(1):101-104.
Lowe et al., Cell (1990) 63:475-484.
Brandley et al., Cell (1990) 63:861-863.
Gnewuch et al., Chem. Rev. (1986) 86:203-238.

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