Method of detecting viral infection in vaccinated animals

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 71, 435 792, 424 932, C12Q 170, A61K 4800, G01N 3353

Patent

active

056019742

ABSTRACT:
Provided are methods for determining whether a vaccinated animal is uninfected or infected with a virulent wild-type virus. Methods, vaccines and viruses are disclosed that are useful to seratologically distinguish infected from uninfected animals in populations of animals vaccinated with a properly incapacitated virus lacking an antigen of the wild-type virus.

REFERENCES:
patent: 4514497 (1985-04-01), Kit et al.
patent: 4609548 (1986-09-01), Kit et al.
patent: 4680176 (1987-07-01), Berns et al.
patent: 4703011 (1987-10-01), Kit et al.
patent: 4711850 (1987-12-01), Kit et al.
patent: 4810634 (1989-03-01), Post et al.
patent: 5047237 (1991-09-01), Cochran
patent: 5275934 (1994-01-01), Post et al.
Wathen, M. W. and L. M. K. Wathen, "Isolation, Characterization, and Physical Mapping of a Pseudorabies Virus Mutant Containing Antigenically Altered gp50," J. of Virology 51(1):57-62 (1984).
Holland, T. C. et al., "Antigenic Variants of Herpes Simplex Virus Selected with Glycoprotein-Specific Monoclonal Antibodies," J. of Virology 45(2):672-82 (1983).
Post, L. E. and B. Roizman, "A Generalized Technique for Deletion of Specific Genes in Large Genomes: .alpha. Gene 22 of Herpes Simplex Virus 1 is Not Essential for Growth," Cell 25:227-32 (1981).
Todd, D. and J. B. McFerran, "Control of Aujeszky's Disease," The Veterinary Record 117(24):647 (1985).
Thomsen, D. R. et al., "Replication and Virulence of Pseudorabies Virus Mutants Lacking Glycoprotein gX," J. of Virology 61(1):229-32 (1987).
Sandri-Goldin, R. M. et al., "Method for Induction of Mutations in Physically Defined Regions of the Herpes Simplex Virus Genome," J. of Virology 38(1):41-49 (1981).
Quint, W. et al., "Construction and Characterization of Deletion Mutants of Pseudorabies Virus: A New Generation of `Live` Vaccines," J. Gen. Virol. 68:523-34 (1987).
H. Hampl. et al., "Characterization of the Envelope Proteins of Pseudorabies Virus", J. Virol., 52(2), pp. 583-90 (1984).
T. Ben-Porat and A. S. Kaplan, "Molecular Biology of Pseudorabies Virus", in B. Roizman ed., The Herpesviruses, 3, pp. 105-173 (1984).
A. K. Robbins, et al., "Localization of a Pseudorabies Virus Glycoprotein Gene Using an E. coli Expression Plasmid Library," in Herpesvirus, pp. 551-561 (1984).
Wathen, L. M. K., et al., "Production and Characterization of Monoclonal antibodies Directed Against Pseudorabies Virus", 1985, Virus Research 4:19-29.
Stevely, J. Virol, 16(5):944-950 (Oct. 1975).
Pouwels et al., (1985) in Cloning Vectors. (Elsevier Science Publishers, Amsterdam), pp. I-1, I-3, I-4, I-5, I-7, I-8, V-1, V-I-1, VI-2, VIII-1, VIII-2, VIII-3, VIII-B-b-i-8, VII-1, VII-2.
Robbins et al., J. Virol, 59(3), 635-45, (Sep. 1986).
D. P. Gustafson, "Pesudorabies" in Diseases of Swine, 5th ed., A. D. Leman et al., eds., pp. 209-223 (1981).
T. C. Jones and R. D. Hunt, "Pseudorabies" in Veterinary Pathology, 5th ed., Lea & Febiger, pp. 322-326 (1983).
C. E. Aronson, ed., Veterinary Pharmaceuticals and Biologicals, 15/98-99 (1983).
T. Ben-Porat and A. S. Kaplan, "Synthesis of Protein in Cells Infected with Herpesvirus" in Virology, 41, pp. 265-273 (1970).
A. S. Kaplan and T. Ben-Porat, "Synthesis of Proteins in Cells Infected with Herpesvirus, VI. Characterization of the Proteins of the Viral Membrane" in Proc. Natl. Acad. Sci. USA, 66, pp. 799-806 (1970).
B. Norrild and B. F. Vestergaard, "Immunoelectrophoretic Identification and Purification of Herpes Simplex Virus Antigens . . . " Intervirology, 11, pp. 104-110 (1979).
R. E. Randall, et al., "Glycoproteins with Type Common and Type Specific Antigenic Sites Excreted from Cells Infected with Herpes Simplex" in J. Gen. Virol., 48, pp. 297-310 (1980).
D. Van Zaane, et al., "Molecular-Biological Characterization of Marek's Dieease Virus" in Virology 121, pp. 116-132 (1982).
R. E. Randall and R. W. Honess, "Proteins of Herpesvirus Saimiri: Identification of Two Virus Polypeptides Released into the Culture Medium of Productively Infected Cells" in J. Gen. Virol., 51, pp. 445-449 (1980).
T. Ben-Porat and A. S. Kaplan, "Synthesis of Proteins in Cells Infected with Herpesvirus" in Virology, 41, pp. 265-273 (1970).
T. J. Rea, et al., "Mapping and Sequence of the Gene for the Pseudorabies Virus Glycoprotein which Accumulates in the Medium of Infected Cells" in J. Virol., 54, pp. 21-29 (1985).
A. L. J. Gielkens, et al., "Genome Differences Among Field Isolates and Vaccine Strains of Pseudorabies Virus," J. Gen. Virol., 66, pp. 69-82 (1985).
B. Lomniczi, et al., "Deletions in the Genomes of Pseudorabies Virus Vaccine Strains and Existence of Four Isomers of the Genomes," J. Virol., 49, pp. 970-979 (1984).
T. C. Mettenleiter, et al., "Mapping of the Structural Gene of Pseudorabies Virus Glycoprotein A and Identification of Two Non-Glycosylated Precursor Polypeptides," J. Virol., 53, pp. 52-57 (1985).
G. Tatarov, "Apathogenic Mutant of the Aujeszky Virus Induced by 5-Iodo-2-Deoxyuridine (IUDR)." Zentralblatt Veterinarmedizin, 15, pp. 847-853 (1968) (translation).
V. Khristova, et al., "Thymidine Kinase Activity of Virulent and Vaccinal Strains of Aujeszky's Disease Virus," Veterinary Science, 22, pp. 15-22 (1982) (translation).
Pablo Valenzuela, et al., "Antigen Engineering in Yeast: Synthesis and Assembly of Hybrid Hepatitis B Surface Antigen-Herpes Simplex 1 gD Particles," Biotechnology, 3, pp. 323-326 (1985).
M. P. Kieny, et al., "Expression of rabies virus glycoprotein from a recombinant vaccinia virus," Nature, 312, pp. 163-166 (1984).
T. C. Mettenleiter, et al., "Pseudorabies Virus Avirulent Strains Fail to Express a Major Glycoprotein," Journal of Virology, 56, pp. 307-311 (1985).
Davison et al, Chapter 7, pp. 103-124, in Recombinant DNA Research and Viruses, Becker, ed, 1985.
Thomsen et al, J. Virol, 61(1), 229-32, 1987 (Jan).
Petrovskis et al, J. Virol, 60(3), 1166-9, 1986 (Dec.).
Robbins et al, J. Virol., 59(3), 635-45, 1986 (Sep.).
Ben-Porat et al, J. Virol., 57(1), 191-6, (Jan. 1986).
Mettlenleiter et al, J. Virol., 56(1), 307-11, (Oct. 1985).
Ben-Porat et al, Chapter 3 in Molecular Biol. of PRV, pp. 107-173, (1984).
Post et al, Cell, 25, 227-32, (Jul. 1981).
Lomniczi et al, J. Virol., 49(3), 970-9, (Mar. 1984).
Holland et al, J. Virol., 45(2), 672-82, (Feb. 1983).
Roizman et al, Science, 229, 1208-14, (Sep. 1985).
Marchioli et al, Am J. Vet. Res., 48(11), 1577-83, (1987).
Sandri-Goldin et al, J. Virol., 38(1), 41-9, (1981).
Thompsen et al, J. Virol., 61(1), 229-32, (1987).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of detecting viral infection in vaccinated animals does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of detecting viral infection in vaccinated animals, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detecting viral infection in vaccinated animals will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-340983

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.