Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1992-03-09
1994-01-04
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 71, 435 792, 424 89, G01N 33569, G01N 33543, A61K 39245
Patent
active
052759342
ABSTRACT:
Provided are methods for determining whether a vaccinated animal is uninfected or infected with a virulent wild-type virus. Methods, vaccines and viruses are disclosed that are useful to seratologically distinguish infected from uninfected animals in populations of animals vaccinated with a properly incapacitated virus lacking an antigen of the wild-type virus.
REFERENCES:
patent: 4514497 (1985-04-01), Kit et al.
patent: 4609548 (1986-09-01), Kit et al.
patent: 4680176 (1987-07-01), Berns et al.
patent: 4711850 (1987-12-01), Kit et al.
patent: 4810634 (1989-03-01), Post et al.
patent: 5047237 (1991-09-01), Cochran
H. Hampl, et al., "Characterization of the Envelope Proteins of Pseudorabies Virus", J. Virol., 52(2), pp. 583-90 (1984).
T. Ben-Porat and A. S. Kaplan, "Molecular Biology of Pseudorabies Virus", in B. Roizman ed., The Herpesviruses, 3, pp. 105-73 (1984).
A. K. Robbins, et al., "Localization of a Pseudorabies Virus Glycoprotein Gene Using an E. coli Expression Plasmid Library", in Herpesvirus, pp. 551-61 (1984).
Wathen, L. M. K., et al., "Production and Characterization of Monoclonal antibodies Directed Against Pseudorabies Virus", 1985, Virus Research 4:19-29.
Stevely, J. Virol. 16(5):944-950 (Oct. 1975).
Pouwels et al., (1985) in Cloning Vectors, (Elsevier Science Publishers, Amsterdam), pp. I-1, I-3, I-4, I-5, I-7, I-8, V-1, V-I-1, VI-2, VIII-1, VIII-2, VIII-3, VIII-B-b-i-8, VII-1, VII-2.
Robbins et al., J. Virol. 59(3), 635-45, (Sep. 1986).
D. P. Gustafson, "Pseudorabies", in Diseases of Swine, 5th ed., A. D. Leman et al., 209-23 (1981).
Jones, T. C. and R. D. Hunt, "Pseudorabies (Infectious Bulbar Paralysis, Aujeszky's Disease, Mad Itch) in Veterinary Pathology", 5th Ed., Lea & Febiger, 322-26(1983).
C. E. Aronson, "Pseudo-Cine.TM.with Havlogen.RTM.", Veterinary Pharmaceuticals & Biologicals 15/90 (1982-1983).
C. E. Aronson, "PR-VAC.RTM.", and PR-VAC.RTM.-Killed, and PR-VAC.RTM./Leptoferm-5, Veterinary Pharmaceuticals & Biologicals 15/98-99(1982-1983).
Ben-Porat, T. and A. S. Kaplan, "Synthesis of Proteins in Cells Infected with Herpesvirus V. Viral Glycoproteins", Virology 41:265-73(1970).
Kaplan, A. S. and T. Ben-Porat, "Synthesis of Proteins in Cells Infected with Herpesvirus, VI. Characterization of the Proteins of the Viral Membrane", Proc. of Natn'l Acad. of Sciences 66(3):799-806(1970).
Norid, B. and B. F. Vestergaard, "Immunoelectrophoretic Identification and Purification of Herpes Simplex Virus Antigens Released from Infected Cells in Tissue Culture", Intervirology 11:104-10(1979).
Khristova, V. et al., "Thymidine Kinase Activity of Virulent and Vaccinal Strains of Aujezsky's Disease Virus", Veterinary Science XXII(3):15-22.
G. Tatarov, "Apathogenic Mutant of the Aujeszky Virus Induced by 5-Iodo-2-Deoxyuridien (IUDR)", Zentralblatt Veterinarmedizin 15:847-53(1968).
Randall, R. E. et al., "Glycoproteins with Type Common and Type Specific Antigenic Sites Excreted from Cells Infected with Herpes Simplex Virus Types 1 and 2", J. Gen. Virol. 48:297-310 (1980).
VanZaane, D. et al., "Molecular-Biological Characterization of Marek's Disease Virus", Virology 121:116-32(1982).
Randall, R. E. and R. W. Honess, "Proteins of Herpesvirus Saimiri:Identification of Two Virus Polypeptides Released into the Culture Medium of Productively Infected Cells", J. Gen. Virol. 51:445-49(1980).
Ben-Porat, T. and A. S. Kaplan, "Synthesis of Proteins in Cells Infected with Herpesvirus", Virology 41:265-73(1970).
Rea, T. J. et al., "Mapping and Sequence of the Gene for the Pseudorabies Virus Glycoprotein Which Accummulates in the Medium of Infected Cells", J. of Virology 54(1):21-29(1985).
Gielkens, A. L. J. et al., "Genome Differences Among Field Isolates and Vaccine Strains of Pseudorabies Virus", J. Gen. Virol. 66:69-82(1985).
Lomniczi, B. et al., "Deletions in the Genomes of Pseudorabies Virus Vaccine Strains and Existence of Four Isomers of the Genomes", J. of Virology 49(3):970-79(1984).
Mettenleiter, T. C. et al., "Mapping of the Structural Gene of Pseudorabies Virus Glycoprotein A and Identification of Two Non-Glycosylated Precursor Polypeptides", J. of Virology of 53(1):52-57(1985).
Valenzuela, P. et al., "Antigen Engineering in Yeast:Synthesis and Assembly of Hybrid Hepatitis B Surface Antigen-Herpes Simplex 1 gD Particles", Bio/Technology 3:323-26(1985).
Kieny, M. P. et al., "Expression of Rabies Virus Glycoprotein From a Recombinant Vaccinia Virus", Nature 312:163-66(1984).
Mettenleiter, T. C. et al., "Pseudorabies Virus Avirulent Strains Fail to Express a Major Glycoprotein", J. of Virology 56(1):307-11(1985).
Wathen, M. W. and L. M. K. Wathen, "Isolation, Characterization, and Physical Mapping of a Pseudorabies Virus Mutant Containing Antigenically Altered gp50", J. of Virology 51(1):57-62(1984).
Holland, T. C. et al., "Antigenic Variants of Herpes Simplex Virus Selected with Glycoprotein-Specific Monoclonal Antibodies", J. of Virology 45(2):672-82(1983).
Post, L. E. and B. Roizman, "A Generalized Technique for Deletion of Specific Genes in Large Genomes: .alpha.Gene 22 of Herpes Simplex Virus 1 is Not Essential for Growth", Cell 25:227-32(1981).
Todd, D. and J. B. McFerran, "Control of Aujeszky's Disease", The Veterinary Record 117(24):647(1985).
Thomsen, D. R. et al., "Replication and Virulence of Pseudorabies Virus Mutants Lacking Glycoprotein gX", J. of Virology 61(1):229-32(1987).
Sandri-Goldin, R. M. et al., "Method for Induction of Mutations in Physically Defined Regions of the Herpes Simplex Virus Genome", J. of Virology 38(1):41-49(1981).
Quint, W. et al., "Construction and Characterization of Deletion Mutants of Pseudorabies Virus: A New Generation of 'Live' Vaccines", J. Gen. Virol. 68:523-34(1987).
Post Leonard E.
Thomsen Darrell R.
Carter Philip W.
Koivuniemi Paul J.
Schwartz Richard A.
Steele Gregory W.
The Upjohn Company
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