Method of detecting variant nucleic acids using extension oligon

Details Method of detecting variant nucleic acids using extension oligon Method of detecting variant nucleic acids using extension oligon

1996-03-06

1998-03-17

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 911, C12Q 168, C12P 1934

Patent

active

057285306

ABSTRACT:
Method of detecting nucleic acids whose nucleotide sequences differ from one another at a position X. The method uses a set of oligonucleotides where the nucleotides found at position X are complementary to a variant nucleic acids only at this position X. However, with respect to the position of another mismatch Y, the nucleotide sequences thereof differ from one another. The invention further addresses reagents for performing the methods as well as reagents and applications of the method.

REFERENCES:
Newton et al., Nucleic Acids Res. 17(7), 2503-2516 (1989).
Oncogene Res. 1, 235-241 (1989).
Nucleic Acids Res. 17, 8093-8099 (1989).
Nucleic Acids Res. 18, 999-1005 (1990).
Biochem. Biophys. Res. Comm. 160, 441-447 (1989).
Proc. Natl. Acad. Sci. USA 82, 1585-1588 (1985).
New England J. Med. 317, 985 (1987).
Nucleic Acids Res. 17, 2437-2448 (1989).
Proc. Natl. Acad Sci. USA 88, 189-193 (1991).
Nucleic Acids Res. 16, 11141-11151 (1988).

Affiliated with

Also associated with

Rating

Method of detecting variant nucleic acids using extension oligon does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of detecting variant nucleic acids using extension oligon, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detecting variant nucleic acids using extension oligon will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-956461