Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-04-21
1996-11-19
Wax, Robert A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 29, 435 32, 43525233, 435849, 435 72, 435 737, 435 76, C12Q 168, C12Q 102, C12Q 118, C12N 120
Patent
active
055761798
ABSTRACT:
A protein and gene encoding it are disclosed which confer sensitivity to B. maydis T toxin and the insecticide methomyl, in cells carrying the gene and expressing the protein. Toxin sensitivity domains of the protein have been identified wherein a modification yields a toxin-insensitive product.
REFERENCES:
Dewey, R. E., C. S. Levings III, D. H. Timothy (1986) "Novel Recombinations in the Maize Mitochondiral Genome Produce a Unique Transcriptional Unit in the Texas Male-Sterile Cytoplasm" Cell 44:439-449.
Dewey, R. E., D. H. Timothy, C. S. Levings III (1987) "A mitocondrial protein associated with cytoplasmic male sterility in the T cytoplasm of maize" Proc. Natl. Acad. Sci. USA 84:5374-5378.
Wise, R. P., D. R. Pring, B. G. Gengenbach (1987) "Mutation to male fertility and toxin insensitivity in Texas (T)-cytoplasm maize is associated with a frameshift in a mitochondiral open reading frame" Proc. Natl. Acad. Sci. USA 84:2858-2862.
Forde, B. G., C. J. Leaver (1980) "Nuclear and cytoplasmic genes controlling synthesis of variant mitochondrial polypeptides in male-sterile maize" Proc. Natl. Acad. Sci. USA 77:418-422.
Umbeck, P. F., B. G. Gengenbach (1983) "Reversion of Male-Sterile T-Cytoplasm Maize to Male Fertility in Tissue Culture" Crop Science 23:584-588.
Braun, C. J., J. N. Siedow, C. S. Levings III (1989) "The T-urf13 Gene is Responsible for Toxin Sensitivity in Maize and E. coli" The Molecular Basis of Plant Development, pp. 79-85.
Huang et al. Expression in yeast of the T-URF13 protein from Texas male-sterile maize mitochondria confers sensitivity to methomyl and to Texas-cytoplasm-specific fungal toxins. EMBO J. vol. 9, No. 2, pp. 339-347. 1990.
Allmen et al. Transfer of methomyl and HmT-toxin sensitivity from T-cytoplasm maize to tobacco. Mol. Gen. Genet. vol. 229, pp. 405-412. 1991.
Wise et al. urf13-T of T cytoplasm maize mitochondria encodes a 13 kD polypeptide. Plant Molecular Biology. vol. 9, pp. 121-126. 1987.
Dewey et al. A 13-kilodalton maize mitochondrial protein in E. coli confers sensitivity to Bipolaris maydis toxin. Science. vol. 239, pp. 293-295. Jan. 15, 1988.
Simmon et al. In vitro mutagenic studies of twenty pesticides. Toxicol. Appl. Pharmacol. vol. 31, No. 1, p. 109. 1976.
Klein et al. Mode of methomyl and Bipolaris maydis (race T) toxin in uncoupling Texas male-sterile cytoplasm corn mitochondria. Plant Physiology. vol. 77, pp. 912-916. 1985.
Aranda et al. Methomyl analogs with increased biological activity towards F7T maize mitochondria. Phytochemistry. vol. 26, No. 7, pp. 1909-1913. 1987.
Braun Carl J.
Dewey Ralph E.
Levings, III Charles S.
Lathrop Brian K.
Mycogen Plant Sciences, Inc.
North Carolina State University
Wax Robert A.
LandOfFree
Method of detecting toxin-insensitive urf13-T protein does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of detecting toxin-insensitive urf13-T protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detecting toxin-insensitive urf13-T protein will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-540136