Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-03-01
1997-08-26
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 435 721, 435268, 4351722, 435272, 435330, 435331, 435332, 435344, 436543, 436544, 436548, 436 84, 436815, 530350, 530353, 530357, 5303877, 53038885, G01N 33574
Patent
active
056609949
ABSTRACT:
The invention relates to the identification of insoluble cytoskeletal proteins, or fragments thereof, which are characteristic of the origin of the tissue. The invention relates as well to the method for detecting such proteins by breaking down and solubilizing the protein for immunological detection and quantitation. The method allows detection of tissue lesions or other pathological foci and metastases.
REFERENCES:
patent: 4169138 (1979-09-01), Jonsson
patent: 4299916 (1981-11-01), Litman et al.
patent: 4727021 (1988-02-01), Cote et al.
patent: 4775620 (1988-10-01), Cardiff et al.
patent: 4952507 (1990-08-01), Woodward
Nelson, W., et al., Cancer Res., 44:1600-1603 (1984).
Roop, D. et al., Journ Biol Chem., 259(13):8037-8040 (1984).
Jorcano. J. et al. Journ Mol. Biol., 179:257-281 (1984).
Hintner, H. et al, Journ Clin Invest. 71:1344-1351 (1983).
Tseng, S. et al., Cell 30:361-372 (1982).
Gigi, O. et al., EMBO Journ. L Noll:1429-1437 (1982).
Geisler, N. et al., Cell 30:277-286 (1982).
Von Kosbull, H. et al., Biol Abstr. 74(5), (1982) Abstr #30655.
Woodcock-Mitchell, J. et al. Chem. Abstr. 97 (1982) abstr #211794c.
Weber, K. et al., Biol Abstr., 72(3) (1981), Abstr #17437.
Cremer, M. et al, Biol Abstr. 72(4) (1981), Abstr #22764.
Achstaetter, T., et al., Biol Abstr 83(1) (1987) Abstr. #5344.
Hintner et al., J. Clin. Invest. 71:1344-1351 (1983).
Weber et al., EMBO J. 3:2707-2714 (1984).
Osborn et al., TIBS 11:469-72 (1986).
Albrechtsen et al., J. Neuroimmunol 8:301-309 (1985) Abst. Only.
Getslor et al., "Neurofilament Architecture . . . Triplet Proteins," EMBO J.2:1295-1302 (1983).
Albrechtsen et al., "Glial Fibrillary Acidic . . . Neural Tube Defects," Prenatal Diagnosis 4:405-410 (1984).
Albrechtsen et al., "Quantification of Glial Fibrillary . . . Monoclonal Antibody," J. Neuro Immunol 8:301-309 (1985).
Van Regemorter et al., "Value of Glial Fibrillary Acidic . . . Noural Tube Defects," Clin Chim Acta 165:83-88 (1987).
Chem et al., "Presence of proteoly finally processed Keratins in the culture . . . ," Cancer Research 46:6353-59 (1986).
Mellerick et al., "On the nature of serological tissue polypeptide . . . ," Oncogene 5:1007-1017 (1990).
Dellagi et al., "Human Monoclonal IgM With Autoantibody Activity Against Intermediate Filaments", Proc. Natl. Acad. Sci. USA. vol. 79, Jan. 1982, pp. 446-450.
Osung et al., "Antibody to Intermediate Filaments of the Cytoskeleton in Rheumatoid Arthritis", Ann. Rhea. Dis. (England) vol. 41/1 1982 pp. 69-73 (Abstract).
Senecal et al., "Immunoglobin M Autoantibody to Vimentin Intermediate Filaments", J. Clin. Invest., vol. 69, Mar. 1982, pp. 716-772.
Hansson et al., "Fc-mediated binding of IgG to Vimentin-Type Intermediate Filaments in Vascular Endothelial Cells" Proc. Natl. Acad. Sci. USA vol. 81 (10), May 1984, pp. 3103-3107 (Abstract).
Paulin et al., "In Vitro differentiation of Mouse Teratocarcinoma Cells Monitored by Intermediate Filament Expression", Differentiation, vol. 22 (2), 1982, pp. 90-99 (Abstract).
Bjorklund et al., Tumormarkersystem CEA-TPA, Luthgens M. und Schlegel G., eds. TumorDiagnostick Verlag, Leonberg, S., pp. 14-29 (1987).
Leube et al, Differentiation, 33:69-85 (1986).
Chemical Abstracts, Band 95, 1981, Seite 302, Nr. 37953a, Columbus, Ohio; Nelson et al.: "Properties of a Calcium Ion-activated protoase specific for the intermediate-sized filament protein vimentin in Ehrlich ascites tumor cells", & Eur. J. Biochem. 1981, 116(1), 51-7.
Virtanen et al., J. Cell Sci. 50:45-63 (1981).
Nachr. Chem. Tech. Lab 35 (1987).
J. Immun. Meth., Band 85, 1985, Seiten 401-407, Elsevier Science Publishers B.V. Amsterdam; Hansson et al: "Solid-phase Preparation of Vimentin-type Intermediate Filaments for Immunoassays".
Chemical Abstracts, Band 96, 1982, Seite 498, Nr. 159850f, Columbus, Ohio; Virtanen et al: "Low-ionic Strength Induces Degradation of Vimentin in Cultured Human Fibroblasts", & Biochem. Biophys. Res. Comm. 1982, 105(2), 730-6.
Kurki and Virtanen, J. Immun. Meth., 67:209-223 (2984).
Chemical Abstracts, Band 96, 1982, Seite 458, Nr. 101416c, Columbus, Ohio; Traub et al: "Occurrence in Various Mammalian Cells and Tissues of the Calcium (2+)-activated Protease Specific for the Intermediate-sized filament Proteins Vimentin and Desmin", & Eur. J. Cell. Biol. 1981, 26(1), 61-7.
Kurki et al., Clin. Immunology and Immunopathology 11:379-387 (1978).
Chemical Abstracts, 101:370462 1984.
Chemical Abstracts, 9631704 1982.
Bruder-Heid Gerda
Franke Werner Wilhelm
Nucker Christine M.
Progen Biotechnik GmbH
Stucker Jeffrey
LandOfFree
Method of detecting tissue-specific, insoluble cytoskeletal prot does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of detecting tissue-specific, insoluble cytoskeletal prot, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detecting tissue-specific, insoluble cytoskeletal prot will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1987465