Method of detecting the concentration of an analyte

Details Method of detecting the concentration of an analyte Method of detecting the concentration of an analyte

2011-06-14

2011-06-14

Toatley, Gregory J (Department: 2877)

Optics: measuring and testing

For light transmission or absorption

By comparison

C356S448000, C356S039000, C600S316000

Reexamination Certificate

active

07961326

ABSTRACT:
A system and method is provided for detecting concentration of an analyte in a fluid. The method comprises detecting an optical property of a first region of two or more regions in a system, the first region located in a container having a reservoir for one or more modifiers of one or more optical properties of the first region. The movement of the one or more modifiers is responsive to changes in concentration of the analyte. A next step detects an optical property of a second region of the two or more regions in the system, the second region located in a container having a reservoir for one or more modifiers of one or more optical properties of the second region. The movement of the one or more modifiers is responsive to changes in concentration of a compound, where the compound is something other than the analyte. The detected optical property of the first region and the detected optical property of the second region are used in embodiments to separate the effect of the analyte on the detected optical property of the first region from the effect of the compound, where the compound is an interfering compound.

REFERENCES:
patent: 4448534 (1984-05-01), Wertz et al.
patent: 5560356 (1996-10-01), Peyman
patent: 6256522 (2001-07-01), Schultz
patent: 6952603 (2005-10-01), Gerber
patent: 7016714 (2006-03-01), Colvin, Jr.
patent: 7043289 (2006-05-01), Fine
patent: 7135342 (2006-11-01), Colvin et al.
patent: 7226414 (2007-06-01), Ballerstadt
patent: 7236812 (2007-06-01), Ballerstadt
patent: 7254429 (2007-08-01), Schurman
patent: 7291824 (2007-11-01), Kiesel
patent: 7358476 (2008-04-01), Kiesel
patent: 2004/0072358 (2004-04-01), Ballerstadt et al.
patent: 2007/0148760 (2007-06-01), Kiesel
patent: 2008/0021293 (2008-01-01), Schurman
patent: 2008/0186483 (2008-08-01), Kiesel
patent: 2008/0186492 (2008-08-01), Kiesel
patent: 2008/0186494 (2008-08-01), Kiesel
patent: 2008/0186500 (2008-08-01), Schmidt
patent: 2008/0186503 (2008-08-01), Kiesel
patent: 1953532 (2008-08-01), None
patent: 1953535 (2008-08-01), None
European Search Report, EP Application No. 09167956.3-1265, Dated Dec. 1, 2009, The Hague.
European Search Report, EP Application No. 09167957.2-1265, Dated Dec. 1, 2009, The Hague.
B. B. Agrawal and I. J. Goldstein. “Specific binding of concanavalin A to cross-linked dextran gels”,Biochemical Journal96(3), 23c-25c (1965).
R. Russell, M. Pishko, C. Gefrides and G. Cote. “A fluorescent glucose assay using poly-L-lysine and calcium alginate microencapsulated TRITC-succinyl-concanavalin A and FITC-dextran”, Pishko, M. 20, 2858-2861 (1998)Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE. Gefrides, C.
R. Ballerstadt and J. S. Schultz. “A fluorescence affinity hollow fiber sensor for continous transdermal glucose monitoring”,Anal.Chem. 72(17), 4185-4192 (2000).
U.S. Appl. No. 11/957,610, filed Dec. 17, 2007, Martini.
R. Ballerstadt, A. Kholodnykh, C. Evans, A. Boretsky, M. Motamedi, A. Gowda and R. McNichols. “Affinity-based turbidity sensor for glucose monitoring by optical coherence tomography: toward the development of an implantable sensor”,Anal.Chem. 79(18), 6965-6974 (2007).
S. Goto, K. Masuda, M. Miura, K. Kanazawa, M. Sasaki, M. Masui, M. Shiramizu, H. Terada and H. Chuman. “Quantitative estimation of interaction between carbohydrates and concanavalin A by surface plasmon resonance biosensor”,Chem.Pharm.Bull.(Tokyo). 50(4), 445-449 (2002).
R. Ballerstadt and J. S. Schultz. “Kinetics of dissolution of Concanavalin A/Dextran sols in response to glucose measured by surface plasmon resonance”,Sensors and Actuators B: Chemical46(1), 50-55 (1998).
O. S. Khalil. “Spectroscopic and clinical aspects of noninvasive glucose measurements”,Clin. Chem. 45(2), 165-177 (1999).
J. L. Wang and G. M. Edelman. “Binding and functional properties of concanavalin A and its derivatives. I. Monovalent, divalent, and tetravalent derivatives stable at physiological pH”,J.Biol.Chem. 253(9), 3000-3007 (1978).
R. Ballerstadt, C. Evans, A. Gowda and R. McNichols. “In vivo performance evaluation of a transdermal near- infrared fluorescence resonance energy transfer affinity sensor for continuous glucose monitoring”,Diabetes Technol.Ther. 8(3), 296-311 (2006).
R. Ballerstadt, A. Gowda and R. McNichols. “Fluorescence resonance energy transfer-based near-infrared fluorescence sensor for glucose monitoring”,Diabetes Technot.Ther. 6(2), 191-200 (2004).
J. J. Kim and K. Park. “Glucose-binding property of pegylated concanavalin A”,Pharm.Res. 18(6), 794-799 (2001).

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