Method of detecting single base substitutions in nucleic acids

Details Method of detecting single base substitutions in nucleic acids Method of detecting single base substitutions in nucleic acids

1988-03-18

1992-02-11

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 27, 935 77, 935 78, C12Q 168, C07H 1512, C12N 1500

Patent

active

050875590

ABSTRACT:
A method for detecting point mutations or base substitutions in a nucleic acid polymer is especially useful for detecting such mutations in the highest melting domain (HMD) of a double-stranded nucleic acid polymer and is particularly suited for use with RNA. The method involves the steps of:

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