Method of detecting PHB in human blood serum

Details Method of detecting PHB in human blood serum Method of detecting PHB in human blood serum

1997-09-29

1999-04-06

Ulm, John

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 772, 5303871, 530413, 5303891, 436512, G01N 3353, G01N 33536, G01N 33537, G01N 33541

Patent

active

058916423

ABSTRACT:
An analytical method for detecting the presence poly-beta-hydroxybutyrate (PHB), which can be used as an indicator of atherosclerotic risk is disclosed. In the method, antibodies to PHB are used to detect the PHB.

REFERENCES:
Steinberg, P., In "Hypercholesterolemia and Atherosclerosis. Pathogenesis and Prevent", Churchill Livingstone, New York, pp. 5-25 (1987).
Epstein, F. H., In "International conference on Atherosclerosis", Carlson, L. A., et al., eds, Raven Press, New York (1978) (pp. 351-356).
Wallace, R. B. and Anderson, R. A., Epidemiol Rev 9:95 (1987).
Kannel, W. B., Am Cardiol 52:9B (1983).
Mahley, R. W., et al., J. Lip. Res. 21:970 (1980).
Dahlen, G. H., et al., Circulation 74:758-65 (1986).
Reardon, M. F., Circulation 71:881-8 (1985).
Dawes, E. A., et al., Adv. Microb. Physiol. 10:135 (1973).
Schubert, P., et al., J. Bacteriol. 170:5837 (1988).
Moskowitz, G. J., et al., Biochemistry 8:2748 (1969).
Packter, N. M., In "Biosynthesis of Acetate-derived Compounds", John Wiley, New York pp. 143-150 (1973).
Reusch, R. N., et al., J. Bacteriol 156:778 (1983).
Reusch, R. N., et al., Proc. Natl. Acad. Sci. USA 85:4176 (1988).
Reusch, R. N., Soc. Exp. Biol. Med. 191:377 (1989).
Tanio, T., et al., Eur. J. Biochem. 124:71-77 (1982).
Engvall and Perlman, Immunoschemistry 8:871 (1971).
Bluhm, T. L., et al., Macromolecules 19:2871 (1986).
Karr, D. G., et al., Appl. Environ. Microbiol. 46:1339 (1983).
Bush, T. L., et al., E. Clin. Chem. 34:8B (1988).
Blackburn, H., In "Hypercholesterolemia and Atherosclerosis" (ed. Steinberg, D., et al.) Churchill Livingstone, New York (1987).
Kelly, J. L. and Kruski, A. W., Meth. in Enz. 128, 170-181 (1986).
Law, J. H. and Slepecky, R. A., J. Bacteriol. 82, 33-36 (1961).
Friedewald, W. T., et al., Clin. Chem. 18, 499-502 (1972).
Current Protocols in Molecular Biology (Ausubel, F. M., Brent, R., Kingstom, R. E. Moore, D. D., Seidman, J. G., Smith, J. A. and Struhl, K. eds).pp. 10.2-10.8 John Wiley & Sons, NY (1989).
Mill, G. L. and Lane, P. A., A Guidebook to lipoprotein technique. pp. 1-76. Elsevier, NY (1984).
Peters, T., Adv. Prot. Chem. 37, 161-245 (1984).
Schwick, H. G. and Haupt, H., in The Plasma Proteins, vol. IV pp. 168-220. Academic Press, NY (1984).
Hay, R., et al., in Biochemistry and Biology of Plasma Lipoproteins (Scanu A. M. and Spector, A. A. eds) pp. 11-51, Marcel Dekker, NY (1986).
Scanu A. M. and Spector, A. A. eds) pp. 1-10, Marcel Dekker, NY (1986).
Eisenberg, S., Meth. in Enz. 129, 347-366 (1986).
Nickerson, K. W., App. Envir. Microbiol. 43, 1208-1209 (1982).
Steiner, G., et al., Meth. in Enz. 129, 395-420 (1986).
Fless, G. M., and Scanu, A. M., in Biochemistry and biology of Plasma Lipoproteins (Scanu, A. M. and Spector A. A. eds) pp. 73-83, Marcel Dekker, NY (1986).
Carter, D. C. and He, X. M., Science 249, 302-303 (1990).

Affiliated with

Also associated with

Rating

Method of detecting PHB in human blood serum does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of detecting PHB in human blood serum, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detecting PHB in human blood serum will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1370108