Method of detecting or identifying virus antigens, erythrocyte o

Chemistry: physical processes – Physical processes – Crystallization

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422 72, 424 11, 424 12, G01N 3354, G01N 3380

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active

042971047

ABSTRACT:
A method for detecting or identifying virus antigens or erythrocyte or cell antigens or antibodies in a biological medium. The reaction of analysis is conducted in a vessel the wall of which has a point of convegence or apex situated on the axis of symmetry of the vessel; the wall of said vessel is coated by molecules with antigenic or antibody activity chosen with respect to the antigen or the antibody to detected; the reaction medium comprising cells or particles and a serum is introduced into the vessel and subjected to a centrifugal force substantially parallel to the aforementioned axis under conditions such that in a first period all the cells or particles, whether they characterize a reaction with a positive result or a negative result, progressively stick to and remain stuck to the wall of the vessel, and then, in a second period, only the cells or particles characterizing one kind of reaction remain stuck to the wall of the vessel by means of said molecules coating said vessel wall, whereas the cells or particles characterizing the other kind of reaction are collected at the apex of the vessel.

REFERENCES:
patent: 4148607 (1979-04-01), Bernoco
"Gradwohl's Clinical Laboratory Methods and Diagnosis", vol. I., S. Frankel et al. eds., 756-757, 302-304, C.V. Mosby Co., Saint Louis, 1970.
N. Henning, "Klinische Laboratoriums Diagnostik, " third edition, pp. 302 to 304, 1966.

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