Method of detecting or determining histamine in histamine contai

Details Method of detecting or determining histamine in histamine contai Method of detecting or determining histamine in histamine contai

1981-09-08

1985-10-29

Turk, Arnold

Chemistry: analytical and immunological testing

Heterocyclic carbon compound

Hetero-n

435 7, 436527, 436541, 436804, 436807, 436811, G01N 3348, G01N 3358

Patent

active

045500851

ABSTRACT:
Histamine is detected or determined selectively in a sample by causing the sample to contact glass microfibers in such a quantitative proportion as will permit the histamine present to bind to the fibers. The amount of bound histamine may be determined by competitive determination in the presence of labelled histamine on the basis of a standard curve, or may be determined directly by conventional coupling reactions.
The method is simple and particularly useful for allergy diagnostics because it exhibits good correlation with known fluorometric methods.

REFERENCES:
patent: 4014651 (1977-03-01), Bettinger et al.
patent: 4020151 (1977-04-01), Bolz et al.
patent: 4256693 (1981-03-01), Kondo et al.
patent: 4297337 (1981-10-01), Mansfield et al.
Bosse et al., Med. Pharmacol. Exp. 16:459-461, (1967).

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