Method of detecting native proBNP

Details Method of detecting native proBNP Method of detecting native proBNP

2007-09-04

2007-09-04

Le, Long V. (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007920, C435S007930, C435S007940, C435S007950, C435S070210, C435S452000, C435S336000, C435S975000, C436S518000, C436S531000, C436S548000, C436S811000, C530S387900, C530S388240, C530S389200, C530S413000

Reexamination Certificate

active

11271138

ABSTRACT:
The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.

REFERENCES:
patent: 5786163 (1998-07-01), Hall
patent: 2003/0219734 (2003-11-01), Buechler
patent: 2004/0096920 (2004-05-01), Davey et al.
patent: 0186799 (1986-07-01), None
patent: 0542255 (1993-05-01), None
patent: WO93/24531 (1993-12-01), None
patent: WO 00/35951 (2000-06-01), None
patent: WO 00/45176 (2000-08-01), None
Buckley, M. et al. “Prolonged stability of brain natriuretic peptide: importance for non-invasive assessment of cardiac function in clinical practice,” Clinical Science (1988) 95, 235-239.
Cleland, J. et al., “Stability of plasma concentrations of N and C terminal atrial natriuretic peptides at room temperature,” Heart 75 (1996) 410-413.
Hughes, D. et al., “An immunoluminometric assay for N-terminal pro-brain natriuretic peptide: a development of a test for left ventricular dysfunction,” Clinical Science (1999) 96, 373-380.
Hunt, P. et al., “The Amino-Terminal Portion of pro-Brain Natriuretic Peptide (Pro-BNP) Circulates in Human Plasma,” Biochemical and Biophysical Research Communications, vol. 215, No. 3 (1995) 1175-1183.
Hunt, P., et al., “Immunoreactive amino-terminal pro-brain natriuretic peptide (NT-PROBNP): a new marker of cardiac impairment,” Clinical Endocrinology (1997) 47, 287-296.
Hunt, P. et al., “The Role of Circulation in Processing pro-Brain Natriuretic Peptide (proBNP) to Amino-Terminal BNP and BNP-32,” Peptides, vol. 18, No. 10 (1997) 1475-1481.
Köhler, G. et al., “Continuous cultures of fused cells secreting antibody of predefined specificity,” Nature 256 (1975) 495-497.
Mair, J. et al., “The Impact of Cardiac Natriuretic Peptide Determination of the Diagnosis and Management of Heart Failure,” Clin. Chem. Lab Med 2001, 39, (7): 571-588.
Mair, J. et al., “Role of Cardiac Natriuretic Peptide Testing in Heart Failure,” Clinical Chemistry 48, No. 7, 2002, 977-978.
Masuta, C. et al., “Cardiac Markers,” Clin. Chem. 44 (1998) 130.
Marrifield, R. et al., Federation of American Societies for Experimental Biology, 46thAnnual Meeting, Atlantic City, NJ, Apr. 14-18, 1962, Abstracts of papers, 412.
Pemberton, C. et al., “Amino-terminal proBNP in ovine plasma: evidence for enhanced secretion in response to cardiac overload,” Am. J. Physiol. 275 (4) Part 2 (1988) H1200-H1208.
Sudoh, T. et al., “A new natriuretic peptide in porcine brain,” Nature 332(Mar. 3, 1988) 78-81.
Tsuji, T. et al., “Stabilization of Human Brain Natriueretic Peptide in Blood Samples,” Clin. Chem. 40 (1994) 672-673.

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