Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-06-07
2000-09-19
Campbell, Eggerton A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 71, C12Q 170, G01N 3353
Patent
active
061209880
ABSTRACT:
Viral proteins derived from an enterically transmitted non-A
on-B viral hepatitis agent (HEV) are disclosed. In one embodiment, the protein is immunologically reactive with antibodies present in individuals infected with the viral hepatitis agent. This protein is useful in a diagnostic method for detecting infection by the enterically transmitted agent. Specific epitopes have been identified that are reactive with sera of individual infected with different strains of HEV. Also disclosed are DNA probes derived from a cloned sequence of the viral agent. These probes are useful for identifying and sequencing the entire viral agent and for assaying the presence of the viral agent in an infected sample, by using probe-specific amplification of virus-derived DNA fragments.
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Bradley Daniel W.
Fry Kirk E.
Krawczynski Krzysztof Z.
Reyes Gregory R.
Tam Albert
Campbell Eggerton A.
Dehlinger Peter J.
Fabian Gary R.
Genelabs Technologies, Inc.
Sholtz Charles K.
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