Method of detecting hepatitis B variants having deletions within

Details Method of detecting hepatitis B variants having deletions within Method of detecting hepatitis B variants having deletions within

1993-06-08

1995-01-03

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 71, 435 792, 435 912, C12Q 170, G01N 3353, C12P 1934

Patent

active

053786050

ABSTRACT:
The present invention provides methods for the detection of hepatitis B virus in atypical infections by simultaneously detecting antibodies against the X and polymerase gene products of HBV. Further, the present invention provides methods for the detection of HBV in atypical infections in a polymerase chain reaction (PCR) assay employing selected primes. These primers allow the detection of a specific class of HBV variants. These methods are useful for demonstrating the presence of productive virus infection and may prove useful in monitoring therapeutics.

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