Method of detecting conditions indicative of atherosclerosis

Details Method of detecting conditions indicative of atherosclerosis Method of detecting conditions indicative of atherosclerosis

1996-09-09

1998-03-24

Alexander, Lyle A.

Chemistry: analytical and immunological testing

Peptide, protein or amino acid

436 89, 436811, G01N 3348

Patent

active

057312087

ABSTRACT:
A diagnostic method and screening test for atherosclerosis and analogous diseases involving activated phagocytes and/or inflammation is provided which comprises determining the presence of p-hydroxyphenylacetaldehyde-lysine in a test sample of a body fluid or tissue at a level which is elevated relative to the level in a normal patient.

REFERENCES:
Berliner and Heinecke, Free Radical Biol. & Med., vol. 20, pp. 707-727 (1996).
Daugherty et al., J. Clin. Invest., vol. 94, pp. 437-444 (1994).
Heinecke et al., J. Biol. Chem., vol. 268, pp. 4069-4077 (1993).
Heinecke et al., J. Clin. Invest., vol. 91, pp. 2866-2872 (1993).
Hazen et al., J. Biol. Chem., vol. 271, pp. 1861-1867 (1996).
Heinecke et al., Biochemistry, vol. 33, pp. 10127-10136 (1994).
Savenkova et al., J. Biol. Chem., vol. 269, pp. 20394-20400 (1994).
Hazen et al., J. Clin. Invest., vol. 98, No. 6, pp. 1283-1289 (1996).
Hazen et al., J. Biol. Chem., vol. 271, No. 38, pp. 23080-23088 (1996).
Heinecke et al., J. Clin. Invest. vol. 77, pp. 757-761 (1986).

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