Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-07-31
2007-07-31
Saunders, David A. (Department: 1644)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C436S503000, C436S504000
Reexamination Certificate
active
10473668
ABSTRACT:
Disclosed is a method of screening a substance for angiotensinogen receptor-modulatory activity. The method includes the steps of contacting placental-derived cells with labeled angiotensinogen and a candidate substance; and then determining whether the candidate substance inhibits the binding of angiotensinogen to the placental-derived cells relative to a control wherein the placental-derived cells are contacted with angiotensinogen in the absence of the candidate substance.
REFERENCES:
patent: 5595882 (1997-01-01), Fujisawa et al.
Petit, A., et al. ; “Angiotensinogen II stimulates both inositol phosphate production and human placental lactogen release from human trophoblastic cells”, J. Clinical Endocrinology and Metabolism, 1989, vol. 69, No. 2, pp. 280-286.
Cell Line Lists, Cell Lines by Tissue Source, ATCC, downloaded Sep. 23, 2006.
DeWitt Ross & Stevens SC
Marshfield Clinic
Sara Charles S.
Saunders David A.
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