Method of detecting analyte-biomolecule interactions

Details Method of detecting analyte-biomolecule interactions Method of detecting analyte-biomolecule interactions

2011-04-26

2011-04-26

Neckel, Alexa D (Department: 1759)

Chemistry: electrical and wave energy

Processes and products

Electrophoresis or electro-osmosis processes and electrolyte...

C204S548000, C204S610000, C204S612000

Reexamination Certificate

active

07931791

ABSTRACT:
The invention provides methods for detecting an interaction between an analyte and a biomolecule. The method comprises separating at least one biomolecule according to its isoelectric point in the presence of a given analyte and detecting an interaction between the analyte and a biomolecule using fluorescence anisotropy. The method may further comprise collecting the analyte-biomolecule complex and analyzing the biomolecule.

REFERENCES:
patent: 5376249 (1994-12-01), Afeyan et al.
patent: 6645733 (2003-11-01), Daksis et al.
patent: 2002/0025576 (2002-02-01), Northrup et al.
patent: 2002/0155106 (2002-10-01), Hammond
patent: 2003/0059811 (2003-03-01), Djaballah et al.
patent: 2004/0029223 (2004-02-01), Karimova et al.
patent: 2004/0058357 (2004-03-01), Soreg et al.
patent: 2004/0096887 (2004-05-01), Ebright et al.
patent: 2004/0106129 (2004-06-01), Crook et al.
patent: 2005/0037418 (2005-02-01), Hamalainen et al.
patent: 2005/0064470 (2005-03-01), Rana
patent: 2005/0244821 (2005-11-01), Zik et al.
Bandilla et al., “Capillary electrochromatography of peptides and proteins”, Journal of Chromatography A, 2004, p. 113-129, vol. 1044, No. 1-2.
Montgomery et al., “Dynamic Isoelectric Focusing for Proteomics” Analytical Chemistry, 2006, pp. 6511-6518, vol. 78.
Svensson, “Isoelectric Fractionation, Analysis, and Characterization of Ampholytes in Natural pH Gradients. I. The Different Equation of Solute Concentrations at a Steady State and its Solution for Simple Cases”, Acta Chemica Scandinavica, 1961, pp. 325-341, vol. 15.

Affiliated with

Also associated with

Rating

Method of detecting analyte-biomolecule interactions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of detecting analyte-biomolecule interactions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detecting analyte-biomolecule interactions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2706136