Method of detecting an expression-enhancing sequence

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S029000

Reexamination Certificate

active

06872524

ABSTRACT:
The invention relates to a method of detecting a DNA sequence which at least partially contributes to promote the stable expression of a gene. To this end the DNA fragment to be examined is cloned in a vector between i) a DNA sequence involved in the induction of gene transcription repressing chromatin, and ii) a reporter gene. The invention also relates to a DNA sequence to be detected by means of the invention, and the application of a stable expression-enhancing DNA sequence for the stable expression of a gene.

REFERENCES:
patent: 5721096 (1998-02-01), Karathanasis et al.
patent: WO 94 29468 (1994-12-01), None
patent: WO 9710337 (1997-03-01), None
patent: WO 98 11207 (1998-03-01), None

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