Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-04-06
1995-09-12
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
536 232, 536 2433, 435 912, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2102, C07H 2104
Patent
active
054496055
ABSTRACT:
The invention relates to a method for detecting the presence of a DNA deletion polymorphism associated with susceptibility for cancer in a human using allele specific amplification primers. Disclosed herein are methods for analyzing human DNA using a hybridization probe which will identify a restriction fragment length polymorphism within the 13q33.fwdarw.qter locus, methods for selectively amplifying DNA within this locus, methods of identifying and producing or purifying the peptide encoded by the human poly (ADP-ribose) polymerase processed pseudogene, and methods of regulating the expression of said processed pseudogene.
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Cherney Barry
Lyn Deborah
Smulson Mark E.
Georgetown University
Zitomer Stephanie W.
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