Method of designing probe from polynucleotide group...

Details Method of designing probe from polynucleotide group... Method of designing probe from polynucleotide group...

2008-01-22

2008-01-22

Shukla, Ram R. (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C435S006120, C536S025300

Reexamination Certificate

active

11259730

ABSTRACT:
There is provided a method of designing a probe from a polynucleotide group comprising a plurality of polynucleotides, the method including: forming a polynucleotide group by selecting polynucleotides having a certain sequence; producing polynucleotide fragments having a certain length from each of the polynucleotides of the polynucleotide group and obtaining sequence and position information on the polynucleotide fragments; providing each polynucleotide fragment with a sequence specific identification number using the obtained sequence and position information of the polynucleotide fragments; and comparing the identification numbers of the fragments to select the probe.

REFERENCES:
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patent: 2004/0157254 (2004-08-01), Kwon
Extended European Search Report for European Application No. 05023049.9-2201.
Meier, H. et al., “Development and implementation of a parallel algorithm for the fast design of oligonucleotide probe sets for diagnostic DNA microarrays,”Concurrency Computat.: Pract. Exper.(2004) 16: 873-893.
Hyndman, D., et al., “Software to Determine Optimal Oligonucleotide Sequences Based on Hybridization Simulation Data,”BioTechniques(1996) 20: 1090-1097.

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