Method of designing multifunctional base sequence

Details Method of designing multifunctional base sequence Method of designing multifunctional base sequence

2007-07-10

2007-07-10

Brusca, John S. (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C536S023100, C530S300000

Reexamination Certificate

active

10746036

ABSTRACT:
A multifunctional base sequence method largely shortens the calculation time and reduces the volume of memory consumption of a processor by carrying out calculation with the advance exclusion of base sequences in which translation termination codons emerge in the second and third reading frames, which are to be excluded in the end. Focusing on the fact that a dipeptide sequence already contains information about the translation products of the second and third reading frames, proteins are analyzed and calculated as duplicated connective products of dipeptide sequences, and are not analyzed as connective products of 20 kinds of amino acids.

REFERENCES:
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patent: 9-322775 (1997-12-01), None
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patent: WO 01/96558 (2001-12-01), None
Shiba et al., “Creation of Libraries with Long ORF's by Polymerization of a Microgene”, Proc. Natl. Acad. Sci. USA, vol. 94, pp. 3805-3810, Apr. 1997.

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