Method of deposition a dry powder and dispensing device

Details Method of deposition a dry powder and dispensing device Method of deposition a dry powder and dispensing device

1998-11-05

2000-11-14

Parker, Fred J.

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

427475, 427486, B05D 104

Patent

active

061466859

ABSTRACT:
A dry powder, for example, a medicament for an inhaler, comprises elongated particles with an aspect ratio sufficient to cause the particles to be bound to a preferably metal or non-metallic sheet material substrate at the particle tips by electrostatic deposition and for aligning a plurality of particles with their major axes aligned normal to the substrate and oriented tip-to-tip. Particles deposited form a low density, high relative void deposition to minimize attractive forces between the particles. This minimizes agglomeration and bonding forces to the substrate facilitating the release of a powdered medicament in an inhaler. Medicament dosages in a substrate pocket are covered by a sealing layer. An embodiment of a drug dosage inhaler substrate and inhaler is disclosed.

REFERENCES:
patent: 5470603 (1995-11-01), Staniforth
patent: 5714007 (1998-02-01), Plelcher et al.

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