Method of denaturing and fragmenting DNA or RNA using...

Chemistry: molecular biology and microbiology – Apparatus

Reexamination Certificate

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Reexamination Certificate

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07625746

ABSTRACT:
A method and apparatus are provided for processing a DNA or RNA sample within a sample processing module. The method includes the steps of providing a sample well within the sample processing module that contains the DNA or RNA sample, coupling ultrasonic energy from an external source into the sampling well and denaturing and fragmenting the DNA or RNA sample using the ultrasonic energy.

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Li et al. (2003) Tsinghua Sceince and Technology vol. 8, No. 4: pp. 487-492.
Belgrader et al. (1999) Anal. Chem 71:4232-4236.

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