Surgery – Means for introducing or removing material from body for... – Treating material applied to or removed from external...
Reexamination Certificate
1998-12-03
2001-02-06
Weiss, John G. (Department: 3761)
Surgery
Means for introducing or removing material from body for...
Treating material applied to or removed from external...
Reexamination Certificate
active
06183451
ABSTRACT:
BACKGROUND OF THE INVENTION
The present invention pertains to the delivery of beneficial agents to skin cells using liposomes in a delivery system. Particularly, the invention involves a system in which skin care compounds are encapsulated in a freeze dried liposome.
The ability of liposomes to encapsulate, carry, and deliver agents to specified cells within the human body is well known. However, little has been done to integrate liposome encapsulated agents into practical skin care procedures and methods. What is needed is a system which combines the beneficial properties of liposomes in practical skin care processes and products.
SUMMARY OF THE INVENTION
It is an objective of the present invention to provide a system for liposome delivery of skin care products which maximized the benefits of liposome technology by increasing shelf life and flexibility of application.
It is another objective of the present invention to provide a method of encapsulating effective agents to be stored and activated at the time of use.
It is another objective of the present invention to provide skin care products in a form which are most effectively carried to the target tissue.
It is also an objective of the present invention to provide a system for application of liposome encapsulated therapeutic agents for enhanced treatment of the skin using a hand held applicator for ease of use.
It is a further objective of the invention to provide an article and method for application of therapeutic agents in freeze-dried liposomes using steam and vapor as a method of rehydration.
It yet another objective of the invention to provide a hand-held applicator to facilitate effective application of agents encapsulated in freeze-dried liposomes.
By encapsulating skin care agents in freeze-dried liposomes the present invention provides a practical method of utilizing the advantages of the liposome structure in effective delivery of skin care products to the skin tissue. This invention takes advantage of the ability of liposomes to deliver agents to specific cells and tissues in the human body. By introducing freeze-drying of liposome encapsulated skin care agents the full benefits of liposome delivery are utilized.
Liposomes especially designed for application to the skin are selected in order to deliver the effective agents to the specific tissue sites requiring treatment. This increases the effectiveness and efficiency of the applied agent. The agents considered include pharmaceutically active compounds including ketoconazole; antioxidants; botanical extracts; alpha hydroxy acids; fruit derived extracts and acids; fragrances; minerals; moisturizers; urea; proteinases such as papain; and vitamins. The liposome encapsulated agents are freeze-dried to improve both shelf-life, increase stability of the liposomes and the encapsulated agents, and add flexibility of application.
In a freeze-dried form, the agents may be effectively applied to the skin in a variety of manners including simple application to the skin by the users fingers. A hand held steam device is introduced to enable more effective application of the freeze-dried liposomes.. This device is designed to provide a supply of steam for reconstitution of the liposomes and agent at the moment of contact with the skin. A fabric pad is also provided on which is deposited a single or multiple freeze-dried liposome encapsulated agents can be secured to the steam device to ease application. Multiple fabric pads may be prepared with a variety of freeze-dried liposomes prior to the time of application and stored allowing for selection at the time of use.
REFERENCES:
patent: 2736317 (1956-02-01), Alexander
patent: 4311712 (1982-01-01), Evans et al.
patent: 4370349 (1983-01-01), Evans et al.
patent: 4830858 (1989-05-01), Payne et al.
patent: 4880635 (1989-11-01), Janoff et al.
patent: 5034228 (1991-07-01), Meybeck et al.
patent: 5106624 (1992-04-01), Bertini
patent: 5128139 (1992-07-01), Brown
patent: 5190762 (1993-03-01), Yarosh
patent: 5439672 (1995-08-01), Zabotto
patent: 5476852 (1995-12-01), Cauwenbergh
patent: 5489426 (1996-02-01), Zabotto
patent: 5607409 (1997-03-01), John
patent: 0160266 (1985-04-01), None
patent: WO 87/01938 (1987-04-01), None
patent: WO87/01938 (1987-05-01), None
patent: WO94/28876 (1994-12-01), None
Mehl, Sr. Thomas L.
Zaias Nardo
Cho David J.
Hanson Sven W.
Weiss John G.
LandOfFree
Method of delivery of skin treatment agents using... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of delivery of skin treatment agents using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of delivery of skin treatment agents using... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2587084