Method of delivery of nucleic acids to peripheral neurons

Details Method of delivery of nucleic acids to peripheral neurons Method of delivery of nucleic acids to peripheral neurons

2005-01-20

2011-10-11

Crouch, Deborah (Department: 1632)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C514S04400A

Reexamination Certificate

active

08034331

ABSTRACT:
The invention provides for methods for delivering a nucleic acid into a peripheral neuron by identifying a target neuron in a dorsal root ganglion and intrathecally delivering a vector comprising the nucleic acid to the dorsal root ganglion neuron. The nucleic acid may encode a neurotrophic factor that may be used to treat a peripheral neuropathy or, in conjunction with a nerve guide conduit, to treat a transected peripheral nerve.

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