Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1984-10-22
1995-08-15
Geist, Gary
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
436829, A61K 9133
Patent
active
054417457
ABSTRACT:
A method is provided for delivering micellular particles containing chemotherapeutic agents and a marker to tumors within a body for the diagnosis and treatment of such tumors. The micellular particles are small, less than 2000 .ANG. and incorporate pure, neutral phospholipid molecules in their external surface. Enhanced delivery of the micellular particles containing marker and chemotherapeutic agents may be achieved by introducing an initial group of positively charged micellular particles to block the reticuloendothelial cells present in the body.
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Presant Cary A.
Proffitt Richard T.
Teplitz Raymond L.
Tin George W.
Williams Lawrence E.
Chapman Lara E.
Geist Gary
Vestar, Inc.
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