Method of delivering a drug using a medical device with a...

Details Method of delivering a drug using a medical device with a... Method of delivering a drug using a medical device with a...

2011-05-10

2011-05-10

Wax, Robert A (Department: 1615)

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

C524S070000, C604S501000, C424S422000

Reexamination Certificate

active

07941212

ABSTRACT:
A method for local delivery of a drug is provided. The method comprises the acts of (a) implanting a medical device carrying a drug-containing coating in a patient for the sustained local delivery of the drug, wherein at least a portion of the coating is transformed from crystalline structure to amorphous structure; and (b) applying an electric current for an interval of time to the device for increasing the rate of release of the drug, wherein the coating is further transformed from crystalline structure to amorphous structure; and (c) terminating the current after an interval of time, wherein at least a portion of the amorphous structure in the coating is at least partially restored to crystalline structure.

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