Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1998-12-15
2000-08-29
Horlick, Kenneth R.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435 6, 435 912, 536 231, 536 2431, 536 2433, C12P 1934, C07H 2102, C07H 2104, C12Q 168
Patent
active
061107115
ABSTRACT:
The invention provides methods and compositions for defining a cell type, generally involving the steps of (a) amplifying the mRNA of a single cell of a heterogenous population of cells; (b) probing a comprehensive expression library with the amplified mRNA to define a gross expression profile of the cell; and (c) comparing the gross expression profile of the cell with a gross expression profile of one or more other cells to define a unique expression profile of the cell, wherein the unique expression profile of the cell provides a marker defining the cell type.
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Ngai John
Serafini Tito
Horlick Kenneth R.
Osman Richard Aron
Siew Jeffrey
The Regents of the University of California
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