Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-05-20
1990-07-17
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514894, A61K 31385
Patent
active
049421727
ABSTRACT:
A method of curing or alleviating hepatic disease comprising administrating to the patient 1,3-dithiole-2-thione or 1,3-dithiolane-2-thione is disclosed. Adminstration of the compound can be made in various dosing forms, including tablets, granules, powders, capsules, suspensions, injections, and suppositories. Normal dosing amount can be determined from the range of 0.01 to 50 mg/kg/day for oral administration, and 0.002 to 10 mg/kg/day for injection or other forms of administration.
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patent: 4034102 (1977-07-01), Taninaka
patent: 4080466 (1978-03-01), Taninaka et al.
patent: 4080467 (1978-03-01), Taninaka et al.
Culvenor, "Reactions of Ethylene Oxide", J. Chem. Soc., pp. 1050-1052, (1946).
Chen, "Easy Synthesis of 1,3 Dithiole-2-Thione", J. Chem. Soc., Chemical Communications, pp. 920-921, (1976).
Irinoda Kazuhiko
Katori Tatsuhiko
Matsuda Hideaki
Nakazawa Hitoshi
Ohtsuka Mari
Gobrogge Roger
Robinson Douglas W.
SS Pharmaceutical Co., Ltd.
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