Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1995-02-23
1995-11-21
Naff, David M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
435212, 435219, 435226, C12P 2102, C12N 948, C12N 950, C12N 964
Patent
active
054686237
ABSTRACT:
A method for converting big endothelin-1 to endothelin-1 by contacting big endothelin-1 with a commercially available preparation of apolipoprotein B is presented. The apolipoprotein B itself has the converting enzyme activity.
REFERENCES:
Ohwaki et al. (1993) Atherosclerosis, 102(2), 227-228.
Ohnaka et al. (1993) J. Biol. Chem., 268(35), 26759-26766.
Ikura et al, (1994) Biochem. Biophys. Res. Comm., 203(3), 1417-1422.
Okada et al. (1990) Biochem Biophys. Res Comm., 171(3), 1192-1198.
Sawamura et al, (1990) Biochem. Biophys. Res Comm., 172(2), 883-889.
Sawamura et al, (1993) Biohim. Biophys. Acta, 1161, 295-302.
Sakai et al. (19 Oct. 93) JP-05,268,956, in Chem Abst, 120, 395, Abst. #72,415.
Sakai (31 Jul. 92) JP-04,210,593, in chem Abst, 117, Abst #229,115.
Knap et al. (1993) J. Cardiovasc. Pharmarol., 22 (Suppl 8), S90-S93, in Chem. Abst., 120(17), 549, Abst. #73,979. Shinmi et al. (1993) J. Cardiovasc. Pharmarol., 22 (Suppl 8), S61-S64, in Chem. Abst., 120(17) 394-395, Abst. #211,159.
Wilkinson et al. (1993) Biochem. Soc. Trans., 21(3), 2765, Sigma Catalog (1990) p. 188, Cat #'s A9159 & A9910.
FEBS Letters, vol. 320, No. 2, pp. 165-168, Apr. 1993, Tatsuya Ohwaki, et al., "Endothelin-Converting Enzyme Activity in Human of Serun Lipoprotein Fraction".
Molecular Biology and Medicine, vol. 6, pp. 65-80, Jan. 23, 1989, James Scott, "The Molecular and Cell Biology of Apolipopritein-B".
Nature, vol. 323, No. 6090, pp. 734-738, Oct. 23, 1986, T. J. Knott, et al., "Complete Protein Sequence and Identification of Structural Domains of Human Apolipoprotein B".
Masashi Yanagisawa, et al., "A Novel Potent Vasoconstrictor Peptide Produced by Vascular Endothelial Cells", Nature, vol. 332, pp. 411-415 (1988).
Kenji Okada, et al., "Conversion of Big Endothelin-1 . . . ", Biochem. Biophys. Res. Commun., vol. 171, No. 3, pp. 1192-1198, 1990.
Tatsuya Sawamura, et al., "Purification and Characterization of Putative Endothelin . . . ", Biochem. Biophys. Res. Commun., vol. 168, No. 3, pp. 1230-1236, 1990.
Issei Komuro, et al, "Endothelin Stimulates c-fos and c-myc Expression . . . ", FEBS Letters, vol. 238, pp. 249-252, 1988.
Kazuo Kanno, et al., "Endothelin-1 and Vasculitis", JAMA, vol. 264, No. 22, p. 2868, 1990.
Amir Lerman, et al., "Circulating and Tissue Endothelin Immunoreactivity . . . ", N. Engl. J. Med., vol. 325, No. 14, pp. 997-1001, 1991.
Takeshi Horio, et al. "Increased Plasma Immonureactive Endothelin-1 . . . ", Atherosclerosis, vol. 89, pp. 239-246, 1991.
Terry J. Opgenorth, et al., "Endothelin-converting Enzymes", FASEB Journal, vol. 6, pp. 2653-2659, 1992.
Ohwaki Tatsuya
Sakai Hiroshi
Naff David M.
Nisshin Flour Milling Co. Ltd.
Weber Jon P.
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