Method of controlling viral growth

Details Method of controlling viral growth Method of controlling viral growth

1994-07-25

1997-05-27

Wax, Robert A.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4352351, C12N 701, C12N 1538

Patent

active

056331525

ABSTRACT:
The present invention relates to a method of specifically inhibiting the growth of a virus, particularly an animal virus, in a permissive host cell comprising introducing into the host cell a virus-related gene encoding a product capable of interacting with the genome of the infecting virus (or a product encoded therein) in a manner such that the life cycle of the infecting virus is disrupted. The invention also relates to a method of rendering a cell, particularly an animal cell, resistant to viral infection, and to a viral resistant cell.

REFERENCES:
patent: 4774182 (1988-09-01), Szybalski
patent: 4859587 (1989-08-01), Roilzman
patent: 5245010 (1993-09-01), Greaves
Preston et al, 1988 Cell 52 425-435.
McKnight et al 1980 Nucleic Acids Research.
Preston et al, Cell 52: 425-434, 1988 (Jan. 12, 1988).
McKnight et al NAR 24:5931. 1980.
Preston et al Cell 52: 425-434, 1988 (Feb. 12, 1988).
McKnight et al NAR 24:5931. 1980.

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