Method of controlling the degradation of glycoprotein oligosacch

Details Method of controlling the degradation of glycoprotein oligosacch Method of controlling the degradation of glycoprotein oligosacch

1995-01-12

1996-04-23

Knode, Marian C.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4352403, 435 701, 514 8, 530395, C12N 500, C12P 2104, A61K 3816, C07K 14435

Patent

active

055102611

ABSTRACT:
A neuraminidase enzyme with unusually high activity under extracellular culture conditions has been discovered in Chinese hamster ovary (CHO) cells and other types of cells. By affecting the neuraminidase activity of the cell culture, the degradation of glycoprotein oligosaccharides produced by these cultured cells can be controlled.

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