Method of controlling lung tumor cell metastasis

Details Method of controlling lung tumor cell metastasis Method of controlling lung tumor cell metastasis

1989-10-02

1992-12-29

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Embryonic structure

514 2, 514 21, 530327, 530328, 530350, 530851, A61K 3550

Patent

active

051750058

ABSTRACT:
A method of controlling tumor cell metastasis comprising administering to a human a therapeutically effective amount of a ribonuclease inhibitor.

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patent: 4966964 (1990-10-01), Shapiro et al.
patent: 5019556 (1991-05-01), Shapiro et al.
"Summary of Results and General Correlations", Cancer Res. Supp., 3, 1-13 (1955).
Geraldi et al., "Selectivity of the Antimetastatic and Cytotoxic Effects of 1-p-3, 3-Dimethyl-1-triazeneno)benzoic Acid Potassium Salt, (.+-.)-1,2-Di(3,5-dioxopiperazin-1-yl)propane, and Cyclophosphamide in Mice Bearing Lewis Lung Carcinoma," Cancer Research, 41, 2524-1548 (1981).
Goldin et al., "Current Results of the Screening Progran at the Division of Cancer Treatment," National Cancer Institute, Europ J. Cancer, vol. 17, pp. 129-142.
Frank S. Lee et al., Primary Structure of Human Placental Ribonuclease Inhibitor, Biochemistry 1988, 27, pp. 8545-8553.
Shapiro et al., "Human placental ribonuclease inhibitor abolishes both angiogenic and ribonucleolytic activities of angiogenin", Apr. 1987, pp. 2238-2241, Proc. Natl. Acad. Sci. vol. 84.
Chemical Abstracts, vol. 109, No. 21, Nov. 21, 1988, p. 282, Abstract 109:185714.

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