Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-05-04
1998-01-27
Wax, Robert A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
424 93461, A01N 3718, A01N 6300
Patent
active
057122482
ABSTRACT:
A novel insecticidal protein isolated from Bacillus thuringiensis var. galleria is described and its DNA sequence is given. This protein, called CryIC(b), is toxic to Lepidoptera, including Spodoptera.
REFERENCES:
patent: 5164180 (1992-11-01), Payne et al.
Chestukhina et al. Bacillus thuringiensis ssp. galleriae simultaneously produces two delta endotoxins differing strongly in primary structure and entomocidal activity. FEBS Letters 232 (1):249-251., May 1988.
Smulevitch et al. Nucleotide sequence of a novel delta endotoxin gene crylg of Bacillus thuringiensis ssp. galleriae. FEBS Letters 293(1,2): 25-28. Nov. 1991.
Bowie et al. Deciphering the message in protein sequences: tolerance to amino acid substitutions. Science 247:1306-1310. , Mar. 1990.
Schnepf, H. et al. 1985 "Amino Acid Sequence of a Crystal Protein from Bacillus thuringiensis Deducted . . . "J. Biol. Chem. 260:6264-6272.
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Hofte, H. et al. 1986 "Structure and Functional Analysis of a Cloned Delta Endotoxin of B. thuringiensis berliner "Eur. J. Biochem. 161:273-280.
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Adang M. et al. 1985 "Characterized Full-Length and Truncated Plasmid Clones of a Crystal Protein . . . "Gene 36:289-300.
Brizzard, B. et al. 1988 "Nucleotide sequence of an additional Crystal Protein Gene Cloned . . . "Nucl. Acids Res. 16(6):2723.
Prefontaine, G. et al., 1987 "Use of Oligonucleotide Probes to Study the Relatedness of Delta-Endotoxin..."Applied & Environ. Micro. 53:2808-2814.
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Kalman Sue S.
Kiehne Kristine L.
Bugaisky G. E.
Marcus-Wyner Lynn
Morris Michael P.
Sandoz Ltd.
Wax Robert A.
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