Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1985-10-30
1987-06-02
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514574, 514885, A61K 3119
Patent
active
046704671
ABSTRACT:
The present invention discloses a method of controlling graft versus host disease, resulting from bone marrow transplantation by treating the host with succinylacetone. A dosage of about 800 mg/kg body weight every 4 days is found optimal.
REFERENCES:
Chemical Abstracts 98:191394n (1983).
Tschudy et al., J. Lab. and Clin. Med. 99:526-632 (1982).
Tschudy et al., Oncology 40:148-154 (1983).
Pendarvis et al., J. Org. Chem. 39:2289-2291 (1974).
Ebert et al., Biochemical and Biophysical Research Communications 88:1382-1390 (1979).
Hess Richard A.
Tschudy Donald P.
Schenkman Leonard
The United States of America as represented by the Secretary of
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