Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1977-11-17
1979-03-06
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424243, 2601125LH, A61K 3156
Patent
active
041431367
ABSTRACT:
A three-phase method of human female contraception wherein (1) starting on about the ninth to about the twelfth day of the female cycle (first cycle day being first menstruation day) an effective amount of at least one progestagenic substance is administered in daily or shorter intervals for about three to about six days followed at substantially similar intervals by (2) administration for about one to about three days starting from about the fourth to about the seventh day after the first phase of both an effective amount of the progestagenic substance(s), and a peptide possessing LHRF (Luteinizing Hormone Release Factor) activity, followed by (3) administration of an effective amount of the progestagenic substance(s) until the total time of the progestagenic substance administration with and without the LHRF compound is from about seven to about fifteen days. A contraceptive preparation or pack comprising a suitable number of dosage units ranging from about seven to about fifteen corresponding with the total time abovementioned, of which the first three to six dosage units contained as hormonal compound only an effective amount of a progestagenic substance, followed by one to three dosage units containing an effective amount of an orally LHRF active peptide in addition to the noted level of progestagenic substance, with the remaining dosage units again containing only the progestagenic substance at the level noted.
REFERENCES:
patent: 3795734 (1974-03-01), Rochefort
patent: 3892723 (1975-07-01), McKinley et al.
patent: 4018919 (1977-04-01), Black
De Jage Evert
DE Visser Jacob
Akzona Incorporated
Falk Robert H.
Roberts Elbert L.
Wendel Charles A.
Young Francis W.
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