Chemistry: analytical and immunological testing – Involving immune complex formed in liquid phase – Separation of immune complex from unbound antigen or antibody
Reexamination Certificate
2006-12-19
2006-12-19
Le, Long V. (Department: 1641)
Chemistry: analytical and immunological testing
Involving immune complex formed in liquid phase
Separation of immune complex from unbound antigen or antibody
C435S007100, C435S173900, C435S287200, C435S962000, C436S906000, C436S518000, C436S524000, C436S528000, C436S536000, C436S538000, C436S166000, C436S174000, C436S177000, C436S016000, C436S017000
Reexamination Certificate
active
07151000
ABSTRACT:
A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected to separation processing (e.g. centrifugation) to obtain serum. The serum is treated with a complexing agent which agent binds prions in the sample forming an agent/protein complex which makes it possible to concentrate the complex. Concentration of the complex results in a sample which can be successfully analyzed, e.g. assayed using a range of different types of assay methodologies for detecting prions.
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Prusiner Stanley B.
Safar Jiri G.
Bozicevic Karl
Bozicevic Field & Francis LLP
Gabel Gailene R.
Le Long V.
The Regents of the University of California
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