Method of coating an intravascular stent with an endothelial cel

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Solid support and method of culturing cells on said solid...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424423, 424 937, 435180, 435396, 435402, 530330, 530402, 530815, C12N 500, C12N 1108, A61F 200, A61K 3808, C07K 1708

Patent

active

061401277

ABSTRACT:
Endothelial cell attachment to an intravascular stent is promoted by coating the stent with an endothelial cell specific adhesion peptide. Coating is preferably carried out by activating the intravascular stent using plasma glow discharge, applying on the stent a layer or plurality of layers of a polymer such as poly(2-hydroxyethylmethacrylate), applying a tresylation solution containing pyridine and tresyl chloride, and applying a five amino acid peptide having the sequence glycine-arginine-glutamic acid-aspartic acid-valine.

REFERENCES:
patent: 4733665 (1988-03-01), Palmaz
patent: 4739762 (1988-04-01), Palmaz
patent: 4776337 (1988-10-01), Palmaz
patent: 5102417 (1992-04-01), Palmaz
patent: 5116318 (1992-05-01), Hillstead
patent: 5195984 (1993-03-01), Schatz
patent: 5278063 (1994-01-01), Hubbell et al.
patent: 5330911 (1994-07-01), Hubbell et al.
patent: 5366472 (1994-11-01), Hillstead
patent: 5476476 (1995-12-01), Hillstead
patent: 5643312 (1997-07-01), Fischell et al.
patent: 5728751 (1998-03-01), Patnaik
D. M. Brunette, The Effects of Implant Surface Topography on the Behavior of Cells; Int. J. Oral Maxillofac Implants, 1988, pp. 231-246, vol. 3.
Campbell Rogers, Elazer R. Edelman, Endovascular Stent Design Dictates Experimental Restenosis And Thrombosis; Circulation, Jun. 15, 1995, pp. 2995-3001, vol. 91, No. 2, American Heart Association, Inc.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of coating an intravascular stent with an endothelial cel does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of coating an intravascular stent with an endothelial cel, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of coating an intravascular stent with an endothelial cel will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2050207

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.