Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1989-02-13
1990-10-02
Lee, Lester L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530303, 530311, 530324, 530333, 530345, 530399, 530409, C07K 112, C07K 310
Patent
active
049608681
ABSTRACT:
A method for cleaving polypeptides at their methionine residue(s) by mean of reaction with cyanogen bromide wherein a solution of guanidium chloride into hydrochloric acid is employed as reaction medium.
REFERENCES:
patent: 4476049 (1984-10-01), Kung
patent: 4721673 (1988-01-01), Uren et al.
White et al., Principles of Biochemistry, 1978, p. 75.
Gross et al., J. Am. Chem. Soc., 1961, vol. 83, pp. 1510-1511.
Canosi Umberto
De Fazio Gabriele
Villa Stefano
Istituto di Ricerca Cesare Serono SpA
Lee Lester L.
Maebius Stephen B.
Williams Stephan P.
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