Method of chromatographic separation

Liquid purification or separation – Processes – Chromatography

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2101982, 127 461, 127 462, B01D 1508

Patent

active

050645390

ABSTRACT:
In a method using a chromatographic separation apparatus consisting of plurality of unit packed beds each having a supply inlet/extraction outlet, wherein the apparatus is effectively divided into four zones; an adsorption zone, a refining zone, a desorption zone, and a concentration zone. A supply and extraction step is performed in which all of the fluid flowing out of the adsorption zone is extracted through the nonadsorbate fluid extraction outlet, and then a recycle step, in which no fluid is supplied to or extracted from the bed, is performed to move the concentration distributions in the bed to a desired position. As a result, the method requires fewer unit beds, and enables extraction of components of higher purity.

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