Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1987-03-19
1992-12-29
Brown, Johnnie R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
536 27, 536 28, 536 29, 514 44, 935 78, C12Q 168, C07H 2104
Patent
active
051750821
ABSTRACT:
Test samples of genomic DNA may be characterized by the use of polynucleotide probes each of which is specific for an informative genetic locus. Such probes may be prepared by the use of probes which are capable of differentiating DNA by reference to more than one polymorphic minisatellite region or hypervariable locus. The polynucleotides and probes of the invention are of use for genetic identification purposes, paternity and maternity testing and particularly in forensic medicine.
REFERENCES:
Nicholls et al, "Direct Cloning of Specific Genomic DNA Sequences in Plasmid Libraries Following Fragment Enrichment", Nucleic Acids Research, 1985, 13, (21), 7569-7578.
Litt et al, "A Highly Polymorphic Locus in Human DNA revealed by Cosmid-Derived Probes", Proc. Natl. Acad. Sci. USA, vol. 82, pp. 6206-6210, Sep. 1985, Genetics.
Nakamura et al, "Variable Number of Tandem Repeat (VNTR) Markers for Human Gene Mapping", Science, 1987, 235, 1616-1622.
Hache et al, "A Rapidly Growing RecBC.sup.- Strain of E. coli Applications for Problem Cloning," Nucleic Acids Research, 1989, 17, (9), 3609.
Wyman et al, "Host Strains That Alleviate Underrepresentation of Specific Sequences: Overview", Methods in Enzymology, 1987, 152, 173-180.
Wong et al., (1987) Ann. Hum. Genetics 51:269-88.
Jeffreys et al., Abstract of Talk to Poultry Research Center, circulated Oct. 22, 1984.
Bell et al., (1981) Proc. Natl. Acad. Sci. 78(9):5759-63.
Goodbourne et al., (1984) Mol. Biol. Med 2:223-8.
Higgs et al., (1986) Proc. Natl Acad. Sci. 83:5165-9.
Jarman et al., (1986) EMBO Journal 5(8):1857-63.
Caskey, (1985) Nature 314:19.
Jeffreys et al., (1985) Nature 314(6006):67-73.
Jeffreys et al., (1985) Nature 316:76-79.
Wong et al., (1986) Nucleic Acids Research 14(11):4605-4616.
Bell et al., (1982) Nature 295:31-35.
Capon et al., (1983) Nature 302:33-37.
Stoker et al., (1985) Nucleic Acids Research 13(13):4613-4622.
Goodbourn et al., (1983) Proc. Natl. Acad. Sci. USA 80:5022-5026.
Wyman et al, (1980) Proc. Natl. Acad. Sci. USA 77(11):6754-6758.
Balazs et al., (1982) Proc. Natl. Acad. Sci. USA 79:7395-7399.
Sykes et al., (1985) Hum. Genet. 70:35-37.
Wyman et al., (1985) Proc. Natl. Acad. Sci. USA 82:2880-2884.
Baird et al., (1986) Am. J. Hum. Genet. 39:489-501.
White et al., (1985) Nature 313:101-105.
Weller et al., (1984) EMBO Journal 3:(2):439-446.
Gill et al., (1985) Nature 318:577-579
Yang et al., (1982) Proc. Natl. Acad. Sci. USA 79:6593-6597.
Proudfoot et al., (1982) Cell 31:553-563.
Beauchamp et al. (1979) Chromosoma (Berl.) 71, 153-166.
Anderson et al. (1981) Nature, 290, 457-465.
Maxam et al. (1977) Proc Natl Acad Sci, 74(2), 560-564.
Sanger et al. (1977) Proc Natl Acad Sci, 74(12) 5463-5467.
Principles of Gene Manipulation, Third Edition, R. W. Old and S. B. Primrose, authors, Blackwell Scientific Publications, 1985, pp. 8-10, 120-121.
Jeffreys et al., (1985) Nature 317:818-819.
Jeffreys et al., (1986) American Journal of Human Genetics 39:11-24.
Crawford et al., (1986) Journal of Medical Genetics 23(5):471.
Yang et al., (1984) Chemical Abstracts 100:118, abstract No. 80593s.
Brown Johnnie R.
Crane L. Eric
Imperial Chemical Industries plc
LandOfFree
Method of characterizing genomic DNA does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of characterizing genomic DNA, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of characterizing genomic DNA will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1886509